Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | CALML3 | P27482 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3334275 | 1.00 | HTT (0.41) | HTTALDH1A1LMNAPOLBTRPV1 | |
| SCHEMBL592115 | 0.88 | HTT (0.47) | HTTALDH1A1LMNAPOLBTRPV1 | |
| SCHEMBL592114 | 0.88 | HTT (0.47) | HTTALDH1A1LMNAPOLBTRPV1 | |
| SCHEMBL3334008 | 0.85 | HTT (0.42) | HTTALDH1A1LMNAPOLBTRPV1 | |
| SCHEMBL1723608 | 0.85 | HTT (0.42) | HTTALDH1A1LMNAPOLBTRPV1 | |
| SCHEMBL3328496 | 0.85 | HTT (0.42) | HTTALDH1A1LMNAPOLBTRPV1 | |
| SCHEMBL2170757 | 0.84 | F10 (0.46) | HTTALDH1A1LMNAPOLBTRPV1 | |
| SCHEMBL592187 | 0.84 | MAOA (0.51) | HTTALDH1A1LMNAPOLBTRPV1 | |
| SCHEMBL592186 | 0.84 | MAOA (0.51) | HTTALDH1A1LMNAPOLBTRPV1 | |
| SCHEMBL590435 | 0.84 | F10 (0.46) | HTTALDH1A1LMNAPOLBTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137290-A1 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD. (CH) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137290-A1 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | OXA1L, XDH, CCNY | HTT 3101/4885ALDH1A1 1130/4885LMNA 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.