Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CPB1 | P15086 | 2/20 | 0.50 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3250014 | 1.00 | ALDH1A1 (0.51) | ALDH1A1GAACPB1SSTR4NAAA | |
| SCHEMBL3250018 | 1.00 | ALDH1A1 (0.51) | ALDH1A1GAACPB1SSTR4NAAA | |
| SCHEMBL3250017 | 1.00 | ALDH1A1 (0.51) | ALDH1A1GAACPB1SSTR4NAAA | |
| SCHEMBL3334317 | 1.00 | ALDH1A1 (0.51) | ALDH1A1GAACPB1SSTR4NAAA | |
| Hydrochloric Acid SCHEMBL25343491 | 0.99 | ALDH1A1 (0.50) | ALDH1A1GAACPB1SSTR4NAAA | |
| SCHEMBL10271774 | 0.90 | ALDH1A1 (0.51) | ALDH1A1GAACPB1NAAATSHR | |
| SCHEMBL16727829 | 0.88 | CPB1 (0.52) | ALDH1A1GAACPB1NAAATSHR | |
| SCHEMBL20274553 | 0.88 | CPB1 (0.52) | ALDH1A1GAACPB1NAAATSHR | |
| SCHEMBL28571314 | 0.88 | CPB1 (0.52) | ALDH1A1GAACPB1NAAATSHR | |
| SCHEMBL16727830 | 0.88 | CPB1 (0.52) | ALDH1A1GAACPB1NAAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144751-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2010-06-10 | — | — | US | disclosed |
| EP-2139888-A2 | IMIDAZOÝ1,2-A¨PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008121687-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144751-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | PIM1, PIM3, PIM2 | ALDH1A1 405/4885GAA 1259/4885CPB1 4283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.