Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 5/20 | 0.52 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | CTSB | P07858 | 3/20 | 0.52 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1763776 | 0.92 | TLR2 (0.52) | TLR2CTSSCTSLCTSBCTSK | |
| Hydrochloric Acid SCHEMBL22462018 | 0.91 | TLR2 (0.53) | TLR2CTSSCTSLCTSBCTSK | |
| SCHEMBL1189554 | 0.91 | CTSS (0.57) | CTSSCTSLCTSBCTSKSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29158039 | 0.89 | CTSS (0.56) | TLR2CTSSCTSLCTSBCTSK | |
| SCHEMBL7818404 | 0.88 | TLR2 (0.53) | TLR2CTSSCTSLCTSBCTSK | |
| SCHEMBL25597451 | 0.86 | TLR2 (0.60) | TLR2CTSSCTSLCTSBCTSK | |
| SCHEMBL29017562 | 0.85 | CTSS (0.49) | TLR2CTSSCTSLCTSBCTSK | |
| SCHEMBL21777615 | 0.85 | CTSS (0.49) | TLR2CTSSCTSLCTSBCTSK | |
| SCHEMBL2746328 | 0.85 | CTSS (0.52) | CTSSCTSLCTSBCTSKSMN1; SMN2 | |
| SCHEMBL5516561 | 0.85 | CTSS (0.52) | CTSSCTSLCTSBCTSKSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144751-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2010-06-10 | — | — | US | disclosed |
| EP-2139888-A2 | IMIDAZOÝ1,2-A¨PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008121687-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2008-10-09 | — | — | WO | disclosed |
| EP-1578743-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2006-11-29 | — | — | EP | disclosed |
| US-20060041123-A1 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2006-02-23 | — | — | US | disclosed |
| EP-1578743-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004058144-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-07-15 | — | — | WO | disclosed |
| EP-0231087-B1 | HEPTANOYL-GLU-ASP-ALA-AMINO ACID IMMUNOSTIMULANTS | PFIZER INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| US-4851388-A | Heptanoyl-glu-asp-ala-amino acid immunostimulants | PFIZER INC. (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0231087-A2 | Heptanoyl-glu-asp-ala-amino acid immunostimulants | PFIZER INC. (US) | 1987-08-05 | — | — | EP | disclosed |
| WO-1987004440-A1 | HEPTANOYL-GLU-ASP-ALA-AMINO ACID IMMUNOSTIMULANTS | PFIZER INC. (US) | 1987-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144751-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | PIM1, PIM3, PIM2 | TLR2 1457/4885CTSS 4604/4885CTSL 4311/4885 |
| US-20060041123-A1 | Antibacterial agents | NQO2, NRDC, IFNG | TLR2 672/4885CTSS 792/4885CTSL 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.