Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CDK4 | P11802 | 4/20 | 0.42 |
| ▸ | CCND1 | P24385 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617408 | 1.00 | TSHR (0.46) | TSHRALDH1A1CDK4CCND1KMT2A | |
| Cyclohexane SCHEMBL3204446 | 0.95 | TSHR (0.43) | TSHRALDH1A1CDK4CCND1KMT2A | |
| SCHEMBL4949474 | 0.82 | LMNA (0.39) | TSHRALDH1A1KMT2AMEN1ALOX5 | |
| SCHEMBL28696512 | 0.82 | CDK4 (0.37) | TSHRALDH1A1CDK4CCND1KMT2A | |
| SCHEMBL29493186 | 0.80 | HTR2A (0.39) | TSHRALDH1A1CDK4CCND1KMT2A | |
| SCHEMBL4954024 | 0.80 | MAOB (0.41) | TSHRALDH1A1ALOX15ALOX5HTR6 | |
| SCHEMBL3576716 | 0.79 | CDK4 (0.47) | TSHRALDH1A1CDK4CCND1KMT2A | |
| SCHEMBL30233726 | 0.79 | CDK4 (0.47) | TSHRALDH1A1CDK4CCND1KMT2A | |
| SCHEMBL4955326 | 0.78 | SRC (0.41) | TSHRALDH1A1 | |
| SCHEMBL4952930 | 0.78 | ROCK1 (0.39) | TSHRALDH1A1ALOX5IDO1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525197-A1 | METHOD FOR PRODUCING HIGHLY PURE HYDROXY INDOLYL GLYOXYLIC ACID AMIDES | Elbion AG (DE) | 2005-04-27 | — | — | EP | claimed |
| WO-2005002337-A1 | DISINFECTANT COMPOSITIONS AND METHODS | VIRTUAL DRUG DEVELOPMENT, INC. (US) | 2005-01-13 | — | — | WO | claimed |
| WO-2004013127-A1 | METHOD FOR PRODUCING HIGHLY PURE HYDROXY INDOLYL GLYOXYLIC ACID AMIDES | ELBION AG (DE) | 2004-02-12 | — | — | WO | claimed |
| CN-113784962-B | Azepino-indoles and other heterocycles for treating brain disorders | 加利福尼亚大学董事会 | 2025-04-25 | — | — | CN | disclosed |
| US-20250051276-A1 | ARYLOXY PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2025-02-13 | — | — | US | disclosed |
| CN-117586645-A | Coloring composition containing dioxazine pigment and color filter | 大塚化学株式会社 | 2024-02-23 | — | — | CN | disclosed |
| WO-2023137518-A1 | PLATINUM COMPLEXES | Western Sydney University (AU) | 2023-07-27 | — | — | WO | disclosed |
| WO-2023114238-A1 | ARYLOXY PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| CN-115490628-A | Preparation method of difluoroethanol compound | 五邑大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-115340484-A | Benzyloxy indole branched-chain acid derivative and its preparation method and use | 上海美迪西生物医药股份有限公司 | 2022-11-15 | — | — | CN | disclosed |
| EP-3307724-B1 | (Z)-2-(1H-INDOL-3-YL)-3-(ISOQUINOLIN-5-YL)ACRYLONITRILE DERIVATIVES AND RELATED COMPOUNDS WITH LYSOSOME INHIBITORY AND ANTI-MITOTIC ACTIVITY FOR TREATING HYPERPROLIFERATIVE DISEASES | NAT UNIV SINGAPORE (SG) | 2020-06-10 | — | — | EP | disclosed |
| EP-0802184-B1 | N-Benzyl-2-phenylindoles as estrogenic agents | WYETH CORP (US) | 2002-06-19 | — | — | EP | disclosed |
| EP-1080073-A1 | COMPOSITIONS COMPRISING 2-PHENYL-INDOLE COMPOUNDS AND ESTROGEN FORMULATIONS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-03-07 | — | — | EP | disclosed |
| WO-2000064917-A2 | SYNTHETIC INDOLOCARBAZOLE REGIOISOMERS AND USES THEREOF | ADVANCED LIFE SCIENCES INC. (US) | 2000-11-02 | — | — | WO | disclosed |
| WO-1999059969-A1 | COMPOSITIONS COMPRISING 2-PHENYL-INDOLE COMPOUNDS AND ESTROGEN FORMULATIONS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-25 | — | — | WO | disclosed |
| EP-0802184-A1 | N-Benzyl-2-phenylindoles as estrogenic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-22 | — | — | EP | disclosed |
| WO-1994025012-A2 | MEDICAMENTS FOR TREATMENT OF MIGRAINE, EPILEPSY AND FEEDING DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1994-11-10 | — | — | WO | disclosed |
| EP-0397060-A2 | Maleinimide derivatives and their use as medicines | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | disclosed |
| EP-0015523-B1 | INDOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR MEDICAMENTS | Dr. Karl Thomae GmbH (DE) | 1982-10-13 | — | — | EP | disclosed |
| EP-0015523-A1 | Indole derivatives, their preparation and their use for medicaments | Dr. Karl Thomae GmbH (DE) | 1980-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051276-A1 | ARYLOXY PSYCHOPLASTOGENS AND USES THEREOF | GRIN2A, GRIN2C, GAP43 | TSHR 2703/4885ALDH1A1 540/4885CDK4 1511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.