⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylformamide SCHEMBL731136 | 1.00 | — | — | |
| Dimethylformamide SCHEMBL17748325 | 0.94 | TSHR (0.56) | — | |
| Dimethylformamide SCHEMBL4814281 | 0.88 | TSHR (0.50) | — | |
| Dimethylformamide SCHEMBL4374569 | 0.86 | TSHR (0.47) | — | |
| Dimethylformamide SCHEMBL10916154 | 0.86 | ALDH1A1 (0.47) | — | |
| Dimethylformamide SCHEMBL23457380 | 0.86 | TSHR (0.47) | — | |
| Dimethylformamide SCHEMBL23282482 | 0.86 | TSHR (0.47) | — | |
| Dimethylformamide SCHEMBL9394570 | 0.84 | — | — | |
| Dimethylformamide SCHEMBL22749119 | 0.84 | — | — | |
| Dimethylformamide SCHEMBL9534280 | 0.84 | TSHR (0.90) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 480 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190683-A1 | METHODS FOR THE TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS | THIOGENESIS THERAPEUTICS, INC. | 2023-06-22 | — | — | US | claimed |
| CN-111592501-B | Synthesis method of 1, 3-oxazine hydroxylate | 遵义医科大学 | 2023-04-07 | — | — | CN | claimed |
| CN-111205301-B | Furan [2,3-c ] chromene derivatives and process for preparing the same | 安徽师范大学 | 2023-02-21 | — | — | CN | claimed |
| CN-111187241-B | Dibenzofurane derivatives and process for producing the same | 安徽师范大学 | 2023-02-21 | — | — | CN | claimed |
| CN-114599639-A | Process for the preparation of 5- (fluoro-4-imino-3-methyl) -1-tosyl-3, 4-dihydropyrimidin- (1H) -one | 阿达玛马克西姆有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-113501791-A | Minoxidil-salicylate crystal form for treating alopecia and preparation method thereof | 山东理工大学 | 2021-10-15 | — | — | CN | claimed |
| CN-113200925-A | Minoxidil crystal form for treating alopecia and preparation method thereof | 山东理工大学 | 2021-08-03 | — | — | CN | claimed |
| WO-2021059160-A1 | PROCESS FOR PREPARING 5-(FLUORO-4-IMINO-3-METHYL)-1-TOSYL-3,4 DIHYDROPYRIMIDINE -(1H)-ONE | ADAMA MAKHTESHIM LTD. (IL) | 2021-04-01 | — | — | WO | claimed |
| CN-111683684-A | Methods for treating cysteamine-sensitive disorders | 硫创治疗公司 | 2020-09-18 | — | — | CN | claimed |
| US-20200268692-A1 | METHODS FOR THE TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS | Prochimia Surfaces SP. Z.o.o. (PL) | 2020-08-27 | — | — | US | claimed |
| CN-101723841-A | Preparation method of 2-amino-5-alkoxy propiophenone | UNIV EAST CHINA NORMAL | 2010-06-09 | — | — | CN | claimed |
| US-7683169-B2 | Crystals of phenylalanine derivatives and production methods thereof | AJINOMOTO CO., INC. (JP) | 2010-03-23 | — | — | US | claimed |
| WO-2009136408-A1 | SYNERGISTIC PHARMACEUTICAL COCRYSTALS | INSTITUTE OF LIFE SCIENCES (IN) | 2009-11-12 | — | — | WO | claimed |
| US-20080171885-A1 | Process for Preparation of Highly Pure Trandolapril | LUPIN LIMITED (IN) | 2008-07-17 | — | — | US | claimed |
| EP-1866327-A1 | IMPROVED PROCESS FOR PREPARATION OF HIGHLY PURE TRANDOLAPRIL | Lupin Ltd. (IN) | 2007-12-19 | — | — | EP | claimed |
| US-20070018172-A1 | Crystals of phenylalanine derivatives and production methods thereof | AJINOMOTO CO., INC (JP) | 2007-01-25 | — | — | US | claimed |
| CN-1886385-A | Crystals of phenylalanine derivatives and production methods thereof | AJINOMOTO KK (JP) | 2006-12-27 | — | — | CN | claimed |
| WO-2006085332-A1 | IMPROVED PROCESS FOR PREPARATION OF HIGHLY PURE TRANDOLAPRIL | LUPIN LIMITED (IN) | 2006-08-17 | — | — | WO | claimed |
| EP-1688410-A1 | CRYSTAL OF PHENYLALANINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Ajinomoto Co., Inc. (JP) | 2006-08-09 | — | — | EP | claimed |
| US-5268524-A | Preparation of linear alkyl aromatics | EXXON CHEMICAL PATENTS INC. (US) | 1993-12-07 | — | — | US | claimed |