SCHEMBL3335814

SCHEMBL3335814

COC(=O)C(C)=CN1CCOCC1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.56
ALDH1A1 P00352 4/20 0.40
GAA P10253 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
MGLL Q99685 1/20 0.38
HSD17B10 Q99714 1/20 0.38
USP2 O75604 2/20 0.38
MAPT P10636 1/20 0.38
ALOX12 P18054 1/20 0.38
GLA P06280 1/20 0.37
HTT P42858 2/20 0.35
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28874538 0.86 RECQL (0.38) RECQLALDH1A1
SCHEMBL29238419 0.84 RECQL (0.37) RECQLALDH1A1SMN1; SMN2HPGDHSD17B10
SCHEMBL3129793 0.81 ALDH1A1 (0.57) RECQLALDH1A1GAAHPGDMAPT
SCHEMBL20805869 0.80 RECQL (0.77) RECQLALDH1A1GAASMN1; SMN2HPGD
SCHEMBL4416632 0.79 SMN1; SMN2 (0.43) RECQLALDH1A1GAASMN1; SMN2HPGD
SCHEMBL340385 0.79 SMN1; SMN2 (0.43) RECQLALDH1A1GAASMN1; SMN2HPGD
SCHEMBL6450597 0.78 RECQL (0.40) RECQLALDH1A1GAASMN1; SMN2HPGD
SCHEMBL9422142 0.77 ALDH1A1 (0.41) RECQLALDH1A1GAASMN1; SMN2HPGD
SCHEMBL150342 0.77 SMN1; SMN2 (0.42) RECQLALDH1A1GAASMN1; SMN2USP2
SCHEMBL609261 0.77 SMN1; SMN2 (0.42) RECQLALDH1A1GAASMN1; SMN2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106471106-B Lubricating oil composition for transmission 捷客斯能源株式会社 2020-03-03 CN disclosed
EP-1908816-B1 BASE OIL FOR HYDRAULIC OIL AND HYDRAULIC OIL COMPOSITIONS NIPPON OIL CORP (JP) 2015-04-29 EP disclosed
US-8735335-B2 Base oil for hydraulic oil and composition using the same NIPPON OIL CORPORATION (JP) 2014-05-27 US disclosed
US-20120172268-A1 BASE OIL FOR HYDRAULIC OIL AND COMPOSITION USING THE SAME NIPPON OIL CORPORATION (JP) 2012-07-05 US disclosed
US-20100144571-A1 BASE OIL FOR HYDRAULIC OIL AND COMPOSITION USING THE SAME NIPPON OIL CORPORATION (JP) 2010-06-10 US disclosed
CN-101454431-A Lubricating oil base oil, preparation method thereof and lubricating oil composition NIPPON OIL CORP (JP) 2009-06-10 CN disclosed
CN-101379171-A Lubricant base oil, lubricating oil composition for internal combustion engine, and lubricating oil composition for transmission device NIPPON OIL CORP (JP) 2009-03-04 CN disclosed
EP-1908816-A1 BASE OIL FOR HYDRAULIC OIL AND HYDRAULIC OIL COMPOSITIONS Nippon Oil Corporation (JP) 2008-04-09 EP disclosed
CN-101058761-A Lubricant compositions for an automatic transmission NIPPON OIL CORP (JP) 2007-10-24 CN disclosed
US-20070197411-A1 Lubricating oil composition SHELL OIL COMPANY 2007-08-23 US disclosed
WO-2007042560-A1 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2007-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100144571-A1 BASE OIL FOR HYDRAULIC OIL AND COMPOSITION USING THE SAME GET3, CPNE4, POLG RECQL 560/4885ALDH1A1 4555/4885GAA 1317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.