SCHEMBL609261

SCHEMBL609261

C/C(=C\N1CCOCC1)C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.42
KDM4E B2RXH2 3/20 0.39
RECQL P46063 1/20 0.39
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
ALDH1A1 P00352 6/20 0.36
GAA P10253 2/20 0.36
MAPT P10636 4/20 0.35
TSHR P16473 2/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
HTT P42858 3/20 0.34
USP2 O75604 2/20 0.33
ALOX12 P18054 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TP53 P04637 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150342 1.00 SMN1; SMN2 (0.42) SMN1; SMN2KDM4ERECQLNPC1RAB9A
SCHEMBL1696446 0.85 TDP1 (0.33)
SCHEMBL6853283 0.83 TDP1 (0.32) L3MBTL1
SCHEMBL5145532 0.83 TDP1 (0.32) L3MBTL1
SCHEMBL340385 0.82 SMN1; SMN2 (0.43) SMN1; SMN2RECQLNPC1RAB9AALDH1A1
SCHEMBL4416632 0.82 SMN1; SMN2 (0.43) SMN1; SMN2RECQLNPC1RAB9AALDH1A1
SCHEMBL489074 0.81 L3MBTL1 (0.34) NPC1ALDH1A1USP2ALOX12L3MBTL1
SCHEMBL842712 0.81 L3MBTL1 (0.34) NPC1ALDH1A1USP2ALOX12L3MBTL1
SCHEMBL27970300 0.79 RECQL (0.37) SMN1; SMN2KDM4ERECQLNPC1RAB9A
SCHEMBL3335814 0.77 RECQL (0.56) SMN1; SMN2RECQLNPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2857446-B1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-03-07 EP disclosed
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
US-20150099823-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-04-09 US disclosed
EP-2857446-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2015-04-08 EP disclosed
US-8334339-B2 Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO., LTD. (JP) 2012-12-18 US disclosed
US-20120041134-A1 CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER COMPOSITION, AND PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed
US-20110207874-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-25 US disclosed