Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27999530 | 0.78 | STAT3 (0.40) | STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL27999496 | 0.78 | STAT3 (0.40) | STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL27547078 | 0.78 | STAT3 (0.40) | STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL30497559 | 0.78 | STAT3 (0.40) | STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL29009077 | 0.78 | STAT3 (0.40) | STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL30657446 | 0.78 | STAT3 (0.40) | STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL9238241 | 0.78 | STAT3 (0.40) | STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL30657448 | 0.78 | STAT3 (0.40) | STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL11327623 | 0.78 | STAT3 (0.40) | STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL6049127 | 0.78 | STAT3 (0.40) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334377-B2 | Porphyrin catalysts and methods of use thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-12-18 | — | — | US | disclosed |
| US-20120283236-A1 | Porphyrin Catalysts and Methods of Use Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-11-08 | — | — | US | disclosed |
| US-8232267-B2 | Porphyrin catalysts and methods of use thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-07-31 | — | — | US | disclosed |
| US-20110306584-A1 | Porphyrin Catalysts and Methods of Use Thereof | TRUSTEES OF PRINCETON (US) | 2011-12-15 | — | — | US | disclosed |
| US-20100093688-A1 | Porphyrin catalysts and methods of use thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-04-15 | — | — | US | disclosed |
| WO-2008094222-A2 | PORPHYRIN CATALYSTS AND METHODS OF USE THEREOF | TRUSTEES OF PRINCETON (US) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008045358-A1 | PORPHYRIN CATALYSTS AND METHODS OF USE THEREOF | TRUSTEES OF PRINCETON (US) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283236-A1 | Porphyrin Catalysts and Methods of Use Thereof | PPOX, POR, MPO | STAT3 1733/4885STAT1 2312/4885MTOR 4567/4885 |
| US-20110306584-A1 | Porphyrin Catalysts and Methods of Use Thereof | PPOX, POR, MPO | STAT3 1387/4885STAT1 2078/4885MTOR 4639/4885 |
| US-20100093688-A1 | Porphyrin catalysts and methods of use thereof | PPOX, POR, MPO | STAT3 1733/4885STAT1 2312/4885MTOR 4567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.