SCHEMBL3336694

SCHEMBL3336694

Clc1ccc(-c2nc3ccccc3[nH]2)c(Cl)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.71
RAB9A P51151 8/20 0.71
ALDH1A1 P00352 7/20 0.71
KDM4E B2RXH2 7/20 0.71
GPR55 Q9Y2T6 1/20 0.71
GUSB P08236 1/20 0.65
NPBWR1 P48145 1/20 0.59
SMN1; SMN2 Q16637 5/20 0.56
PKM P14618 4/20 0.56
HSD17B10 Q99714 3/20 0.56
TP53 P04637 3/20 0.56
NPSR1 Q6W5P4 3/20 0.56
ABCB11 O95342 1/20 0.56
AMY1A P0DUB6 2/20 0.56
HPGD P15428 4/20 0.55
MAPT P10636 4/20 0.55
GAA P10253 3/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
GLA P06280 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30046965 1.00 NPC1 (0.71) NPC1RAB9AALDH1A1KDM4EGPR55
SCHEMBL10041697 0.92 ALDH1A1 (0.65) NPC1RAB9AALDH1A1KDM4EGPR55
SCHEMBL14643717 0.90 NPC1 (0.57) NPC1RAB9AALDH1A1KDM4EGPR55
SCHEMBL12861171 0.87 ALDH1A1 (0.71) NPC1RAB9AALDH1A1KDM4EGPR55
SCHEMBL12861190 0.86 NPC1 (0.74) NPC1RAB9AALDH1A1KDM4EGPR55
SCHEMBL14644293 0.86 NPC1 (0.54) NPC1RAB9AALDH1A1KDM4EGPR55
SCHEMBL7389359 0.86 AMY1A (0.66) NPC1RAB9AALDH1A1KDM4EGPR55
SCHEMBL9888370 0.86 NPC1 (0.69) NPC1RAB9AALDH1A1KDM4EGPR55
SCHEMBL31559156 0.86 AMY1A (0.66) NPC1RAB9AALDH1A1KDM4EGPR55
SCHEMBL10041703 0.86 NPC1 (0.56) NPC1RAB9AALDH1A1KDM4EGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115433929-B Organic solderability copper surface protective agent and preparation method thereof 深圳市豪龙新材料技术有限公司 2023-08-08 CN claimed
CN-115433929-A Organic weldable copper surface protective agent and preparation method thereof 深圳市豪龙新材料技术有限公司 2022-12-06 CN claimed
CN-117835585-B Surface treatment method of circuit board and circuit board manufactured by same 梅州鼎泰电路板有限公司 2024-05-03 CN disclosed
CN-117835585-A Surface treatment method of circuit board and circuit board manufactured by same 梅州鼎泰电路板有限公司 2024-04-05 CN disclosed
CN-115433929-B Organic solderability copper surface protective agent and preparation method thereof 深圳市豪龙新材料技术有限公司 2023-08-08 CN disclosed
CN-115433929-A Organic weldable copper surface protective agent and preparation method thereof 深圳市豪龙新材料技术有限公司 2022-12-06 CN disclosed
CN-109096205-B Synthesis method of benzimidazole compound 五邑大学 2021-08-10 CN disclosed
CN-107312008-B A kind of catalysis prepares the catalyst and system and method for benzimidazole simultaneously [2,1-b] quinoline -6- ketone derivatives 马鞍山市泰博化工科技有限公司 2019-08-27 CN disclosed
CN-107312008-A A kind of easy catalysis prepares the catalyst and system and method for benzimidazole simultaneously ketone derivatives of [2,1 b] quinoline 6 马鞍山市泰博化工科技有限公司 2017-11-03 CN disclosed
CN-106903455-A A kind of high temperature resistant organic solderability preservative and apply usage 长沙理工大学 2017-06-30 CN disclosed
US-8198307-B2 Imidazole derivatives having aryl piperidine substituent, method for preparation thereof and pharmaceutical compositions containing same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2012-06-12 US disclosed
US-20100145054-A1 IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2010-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100145054-A1 IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME TYR, MCHR1, MCHR2 NPC1 223/4885RAB9A 687/4885ALDH1A1 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.