Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 8/20 | 0.74 |
| ▸ | GAA | P10253 | 8/20 | 0.74 |
| ▸ | SI | P14410 | 8/20 | 0.74 |
| ▸ | MGAM2 | Q2M2H8 | 8/20 | 0.74 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | CBFB | Q13951 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6373229 | 0.82 | CBFB (0.63) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL3332631 | 0.80 | MGAM (0.74) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL4788936 | 0.77 | GAA (0.55) | MGAMGAASIMGAM2PIN1 | |
| SCHEMBL29056753 | 0.77 | GAA (0.69) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL3339892 | 0.77 | GUSB (0.73) | MGAMGAASIMGAM2CBFB | |
| SCHEMBL8818524 | 0.75 | MGAM (0.68) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL25722407 | 0.75 | RPS6KA3 (0.58) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL3336441 | 0.74 | KDM4E (0.59) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL6333665 | 0.73 | RPS6KA3 (0.77) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL4113640 | 0.72 | PIN1 (0.64) | MGAMGAASIMGAM2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198307-B2 | Imidazole derivatives having aryl piperidine substituent, method for preparation thereof and pharmaceutical compositions containing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-06-12 | — | — | US | disclosed |
| US-20100145054-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145054-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | TYR, MCHR1, MCHR2 | MGAM 3218/4885GAA 332/4885SI 993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.