Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | SI | P14410 | 1/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.55 |
| ▸ | GUSB | P08236 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6373232 | 0.82 | NPC1 (0.49) | GAAPIN1NPBWR1KDM4EALDH1A1 | |
| SCHEMBL3336702 | 0.77 | MGAM (0.74) | GAAMGAMSIMGAM2GUSB | |
| SCHEMBL3339892 | 0.77 | GUSB (0.73) | GAAMGAMSIMGAM2GUSB | |
| SCHEMBL6333668 | 0.73 | ALDH1A1 (0.53) | GAANPBWR1KDM4EALDH1A1TP53 | |
| SCHEMBL6840289 | 0.72 | PIN1 (0.56) | PIN1NPBWR1KDM4EALDH1A1TP53 | |
| SCHEMBL4113640 | 0.72 | PIN1 (0.64) | GAAMGAMSIMGAM2PIN1 | |
| SCHEMBL4188971 | 0.72 | TRPV1 (0.41) | GAAMGAMSIMGAM2GUSB | |
| SCHEMBL5203546 | 0.72 | ADORA2B (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3711999 | 0.71 | DAO (0.37) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3336441 | 0.71 | KDM4E (0.59) | GAAMGAMSIMGAM2GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140239-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | disclosed |