⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11416625 | 0.69 | — | — | |
| SCHEMBL2351887 | 0.65 | CYP19A1 (0.64) | — | |
| SCHEMBL10349775 | 0.59 | — | — | |
| SCHEMBL10458765 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL2829168 | 0.58 | LTA4H (0.32) | — | |
| SCHEMBL333154 | 0.57 | — | — | |
| SCHEMBL334546 | 0.57 | — | — | |
| SCHEMBL1908087 | 0.57 | — | — | |
| SCHEMBL31030359 | 0.57 | JAK2 (0.33) | — | |
| SCHEMBL11329378 | 0.56 | CNR2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097594-B2 | Macrolides and ketolides having antimicrobial activity | WOCKHARDT LTD. (IN) | 2012-01-17 | — | — | US | disclosed |
| US-20090247478-A1 | Novel macrolides and ketolides having antimicrobial activity | SINDKHEDKAR MILIND DATTATRAYA | 2009-10-01 | — | — | US | disclosed |
| US-7572753-B2 | Tetrazole fungicides | CHEMTURA CORPORATION (US) | 2009-08-11 | — | — | US | disclosed |
| US-20070060631-A1 | 2-cyanomethyl-5-(3-substituted phenyl or 5-substituted thien-2-yl)-2H-tetrazoles; agricultural fungicides such as for rice blast | CROMPTON COLORS INCORPORATED | 2007-03-15 | — | — | US | disclosed |
| EP-0048169-A2 | Bis-tetrazoylmethyl substituted cephalosporin antibiotics, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0048167-A2 | Bis-tetrazolemethyl thiols and their preparation | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0048165-A1 | Bis-tetrazolemethyl substituted beta-lactam antibiotics, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |