Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 6/20 | 0.68 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.68 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.68 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.68 |
| ▸ | ITGAV | P06756 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26128267 | 0.83 | ITGB1 (0.86) | ITGB1ITGA5ITGA4ITGB3ITGAV | |
| SCHEMBL26128274 | 0.83 | ITGB1 (0.86) | ITGB1ITGA5ITGA4ITGB3ITGAV | |
| SCHEMBL26555008 | 0.81 | ITGB1 (1.00) | ITGB1ITGA5ITGA4ITGB3ITGAV | |
| SCHEMBL27043387 | 0.77 | ITGB1 (0.56) | ITGB1ITGA5ITGA4ITGB3ITGAV | |
| SCHEMBL27046057 | 0.77 | ITGB1 (0.56) | ITGB1ITGA5ITGA4ITGB3ITGAV | |
| Trifluoroacetic Acid SCHEMBL26127989 | 0.77 | ITGB1 (1.00) | ITGB1ITGA5ITGA4ITGB3ITGAV | |
| Trifluoroacetic Acid SCHEMBL26127994 | 0.77 | ITGB1 (1.00) | ITGB1ITGA5ITGA4ITGB3ITGAV | |
| SCHEMBL27047850 | 0.75 | ITGB1 (0.56) | ITGB1ITGA5ITGA4ITGB3ITGAV | |
| SCHEMBL30229768 | 0.75 | ITGB1 (0.56) | ITGB1ITGA5ITGA4ITGB3ITGAV | |
| SCHEMBL27047862 | 0.75 | ITGB1 (0.56) | ITGB1ITGA5ITGA4ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144698-A1 | SUBSTITUTED AZETIDINONES | DAIAMED (US) | 2010-06-10 | — | — | US | disclosed |
| US-20090143351-A1 | SUBSTITUTED AZETIDINONES | DAIAMED (US) | 2009-06-04 | — | — | US | disclosed |
| US-7501404-B2 | Substituted azetidinones | DAIMED (US) | 2009-03-10 | — | — | US | disclosed |
| EP-1871741-A2 | SUBSTITUTED AZETIDINONES | Daiamed, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| US-20070105832-A1 | Substituted azetidinones | Cadrenal Therapeutics, Inc. | 2007-05-10 | — | — | US | disclosed |
| WO-2006108039-A2 | SUBSTITUTED AZETIDINONES | DAIAMED, INC. (US) | 2006-10-12 | — | — | WO | disclosed |
| WO-2006108039-A2 | SUBSTITUTED AZETIDINONES | DAIAMED, INC. (US) | 2006-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105832-A1 | Substituted azetidinones | F2R, CPA3, CFD | ITGB1 2797/4885ITGA5 1953/4885ITGA4 2410/4885 |
| US-20100144698-A1 | SUBSTITUTED AZETIDINONES | F2R, CPA3, CFD | ITGB1 2797/4885ITGA5 1953/4885ITGA4 2410/4885 |
| US-20090143351-A1 | SUBSTITUTED AZETIDINONES | F2R, CPA3, CFD | ITGB1 2797/4885ITGA5 1953/4885ITGA4 2410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.