SCHEMBL33378

SCHEMBL33378

C=C(C)C(=O)OCC(COC(=O)c1ccc(C(=O)O)c(C(=O)O)c1)OC(=O)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.52
SERPINE1 P05121 2/20 0.45
ALDH1A1 P00352 3/20 0.42
TSHR P16473 2/20 0.42
MAPK1 P28482 1/20 0.42
PTPN2 P17706 1/20 0.40
PTPN11 Q06124 1/20 0.40
POLB P06746 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.37
CDC25A P30304 1/20 0.35
CDC25B P30305 1/20 0.35
HSD17B10 Q99714 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA7 P43166 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5846246 0.97 PTPN1 (0.48) PTPN1SERPINE1ALDH1A1TSHRMAPK1
SCHEMBL1263713 0.88 PTPN1 (0.65) PTPN1SERPINE1ALDH1A1TSHRMAPK1
SCHEMBL7084792 0.88 POLB (0.41) PTPN1SERPINE1ALDH1A1TSHRMAPK1
SCHEMBL8373670 0.88 ADRB2 (0.41) ALDH1A1TSHRMAPK1POLBTDP1
SCHEMBL15894730 0.85 PTPN1 (0.38) PTPN1SERPINE1ALDH1A1TSHRMAPK1
SCHEMBL13259164 0.84 PTPN1 (0.52) PTPN1SERPINE1ALDH1A1TSHRMAPK1
SCHEMBL10706876 0.84 TSHR (0.45) ALDH1A1TSHRMAPK1POLBTDP1
SCHEMBL11130478 0.84 MAPT (0.41) PTPN1ALDH1A1TSHRMAPK1POLB
SCHEMBL10168303 0.83 POLB (0.43) PTPN1SERPINE1ALDH1A1TSHRMAPK1
SCHEMBL14730856 0.83 TSHR (0.45) PTPN1SERPINE1ALDH1A1TSHRPTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1973587-A2 METHODS AND SYSTEMS FOR PREPARING ANTIMICROBIAL FILMS AND COATINGS Allaccem, Inc. (US) 2008-10-01 EP claimed
WO-2007070801-A2 METHODS AND SYSTEMS FOR PREPARING ANTIMICROBIAL FILMS AND COATINGS ALLACCEM, INC. (US) 2007-06-21 WO claimed
US-7226960-B2 Self-etching primer adhesive and method of use therefor PENTRON CLINICAL TECHNOLOGIES, LLC (US) 2007-06-05 US claimed
US-20030207960-A1 Self-etching primer adhesive and method of use therefor PENTRON CLINICAL TECHNOLOGIES, LLC 2003-11-06 US claimed
US-6326417-B1 CONTAINING SALICYLIC ACID COMPOUND AS MICROBIOCIDES JENERIC/PENTRON INCORPORATED 2001-12-04 US claimed
US-20250340760-A1 ADHESIVE COMPOSITIONS CONTAINING MAGNETIC PARTICLES UNIV KANSAS (US) 2025-11-06 US disclosed
US-12351745-B2 Single-component adhesive compositions OHIO STATE INNOVATION FOUNDATION (US) 2025-07-08 US disclosed
EP-4547771-A1 SHELF STABLE ADHESIVE COMPOSITIONS University of Kansas (US) 2025-05-07 EP disclosed
EP-4547770-A1 ADHESIVE COMPOSITIONS CONTAINING MAGNETIC PARTICLES University of Kansas (US) 2025-05-07 EP disclosed
WO-2024006429-A1 SHELF STABLE ADHESIVE COMPOSITIONS UNIVERSITY OF KANSAS (US) 2024-01-04 WO disclosed
WO-2024006425-A1 ADHESIVE COMPOSITIONS CONTAINING MAGNETIC PARTICLES UNIVERSITY OF KANSAS (US) 2024-01-04 WO disclosed
US-20220135842-A1 SINGLE-COMPONENT ADHESIVE COMPOSITIONS OHIO STATE INNOVATION FOUNDATION 2022-05-05 US disclosed
US-20080020127-A1 Methods and systems for coating a medical device ALLACCEM, INC. 2008-01-24 US disclosed
US-20070202342-A1 Applying to an oral surface (teeth or gums)one or more bridged polycyclic compounds comprising at least two cyclic groups defined in part by quaternary ammonium moieties; microbiocides; self-cleaning; dentistry; bonding agents, resin cements, sealants ALLACCEM, INC. 2007-08-30 US disclosed
WO-2007070801-A2 METHODS AND SYSTEMS FOR PREPARING ANTIMICROBIAL FILMS AND COATINGS ALLACCEM, INC. (US) 2007-06-21 WO disclosed
US-7226960-B2 Self-etching primer adhesive and method of use therefor PENTRON CLINICAL TECHNOLOGIES, LLC (US) 2007-06-05 US disclosed
US-20030207960-A1 Self-etching primer adhesive and method of use therefor PENTRON CLINICAL TECHNOLOGIES, LLC 2003-11-06 US disclosed
US-20020045678-A1 Dental restorative compositions and method of use thereof JENERIC/PENTRON INCORPORATED 2002-04-18 US disclosed
WO-2002015848-A2 DENTAL RESTORATIVE COMPOSITIONS AND METHOD OF USE THEREOF JENERIC/PENTRON INCORPORATED (US) 2002-02-28 WO disclosed
US-6326417-B1 CONTAINING SALICYLIC ACID COMPOUND AS MICROBIOCIDES JENERIC/PENTRON INCORPORATED 2001-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340760-A1 ADHESIVE COMPOSITIONS CONTAINING MAGNETIC PARTICLES FN1, EPCAM, VCL PTPN1 4509/4885SERPINE1 852/4885ALDH1A1 1615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.