SCHEMBL3338044

SCHEMBL3338044

CCO[Si](C)(C)CCCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.47
CHRM2 P08172 1/20 0.47
HTR1A P08908 1/20 0.47
ADRA2A P08913 1/20 0.47
CHRM1 P11229 1/20 0.47
DRD1 P21728 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
ADRA1A P35348 1/20 0.47
OPRM1 P35372 1/20 0.47
DRD3 P35462 1/20 0.47
SLC6A3 Q01959 1/20 0.47
IDO1 P14902 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SIGMAR1 Q99720 3/20 0.39
MAOA P21397 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
AOC3 Q16853 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28731686 0.93 KCNH2 (0.46) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL104845 0.89 TDP1 (0.41) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL1067547 0.85 CHRM2 (0.43) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL15387165 0.83 CHRM2 (0.44) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL4745438 0.82 IDO1 (0.45) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL15737095 0.82 TAAR1 (0.39) L3MBTL1KMT2AAOC3
Hydrogen Sulfide SCHEMBL21291580 0.81 CHRM2 (0.43) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL3342170 0.81 IDO1 (0.44) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL13737894 0.81 CHRM2 (0.40) KCNH2CHRM2HTR1AADRA2ACHRM1
SCHEMBL27878821 0.81 IDO1 (0.46) KCNH2CHRM2HTR1AADRA2ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240027901-A1 PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION USING SAME SAN-APRO LTD. (JP) 2024-01-25 US disclosed
EP-4261214-A1 PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION USING SAME San-Apro Ltd. (JP) 2023-10-18 EP disclosed
CN-111855581-B Method for determining diffusion distance of hardening catalyst 信越化学工业株式会社 2023-04-14 CN disclosed
CN-114660896-A Composition for forming silicon-containing resist underlayer film, pattern forming method, and silicon compound 信越化学工业株式会社 2022-06-24 CN disclosed
WO-2022130796-A1 PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION USING SAME サンアプロ株式会社 2022-06-23 WO disclosed
US-8968458-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2015-03-03 US disclosed
US-8808446-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2014-08-19 US disclosed
CN-101133364-B Composition for resist underlayer film and method for producing same JSR CORP 2013-03-20 CN disclosed
US-20100151384-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2010-06-17 US disclosed
US-20090050020-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2009-02-26 US disclosed
CN-101133364-A Composition for resist underlayer film and method for producing same JSR CORP (JP) 2008-02-27 CN disclosed
EP-1855159-A1 COMPOSITION FOR UNDERLAYER FILM OF RESIST AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2007-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240027901-A1 PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION USING SAME ATIC, MAP1LC3C, TYR KCNH2 1647/4885CHRM2 2845/4885HTR1A 3606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.