⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685410 | 1.00 | — | — | |
| SCHEMBL5956535 | 1.00 | — | — | |
| SCHEMBL2785568 | 0.80 | SLC7A5 (0.55) | — | |
| SCHEMBL41891 | 0.78 | — | — | |
| SCHEMBL7861990 | 0.78 | — | — | |
| SCHEMBL288204 | 0.78 | SLC7A5 (0.52) | — | |
| SCHEMBL10530419 | 0.78 | SLC7A5 (0.52) | — | |
| SCHEMBL7865252 | 0.77 | DPP4 (0.43) | — | |
| SCHEMBL7865250 | 0.77 | DPP4 (0.43) | — | |
| SCHEMBL23455917 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023070120-A1 | KETOAMIDES FOR TREATING MALIGNANCY | BIOTHERYX, INC. (US) | 2023-04-27 | — | — | WO | claimed |
| CN-114502543-A | Targeted protein compounds, pharmaceutical compositions and therapeutic applications thereof | 拜欧斯瑞克斯公司 | 2022-05-13 | — | — | CN | claimed |
| WO-2020242960-A1 | COMPOUNDS TARGETING PROTEINS AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2020-12-03 | — | — | WO | claimed |
| EP-3464285-A1 | PROCESS FOR PREPARING N-(5-(3-(7-(3-FLUOROPHENYL)-3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-INDAZOL-5-YL)PYRIDIN-3-YL)-3-METHYLBUTANAMIDE | Samumed, LLC (US) | 2019-04-10 | — | — | EP | claimed |
| WO-2017210407-A1 | PROCESS FOR PREPARING N-(5-(3-(7-(3-FLUOROPHENYL)-3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-INDAZOL-5-YL)PYRIDIN-3-YL)-3-METHYLBUTANAMIDE | SAMUMED, LLC (US) | 2017-12-07 | — | — | WO | claimed |
| WO-2016154120-A1 | POLYPEPTIDES, PEPTIDES, AND PROTEINS FUNCTIONALIZED BY ALKYLATION OF THIOETHER GROUPS VIA RING-OPENING REACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-09-29 | — | — | WO | claimed |
| US-7687490-B2 | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2010-03-30 | — | — | US | claimed |
| EP-1870412-A1 | 2-THIOETHENYL CARBAPENEM DERIVATIVE | MEIJI SEIKA KAISHA LTD. (JP) | 2007-12-26 | — | — | EP | claimed |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-01-04 | — | — | US | claimed |
| WO-1993011131-A1 | CEPHALOSPORIN COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1993-06-10 | — | — | WO | claimed |
| US-4849419-A | 7-oxo-4-thia-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1989-07-18 | — | — | US | claimed |
| US-4795748-A | Antibacterial 7-oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1989-01-03 | — | — | US | claimed |
| EP-0212404-A1 | 7-oxo-4-thia-1-azabicyclo [3.2.0] hept-2-ene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | claimed |
| EP-0211236-A1 | 7-Oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-02-25 | — | — | EP | claimed |
| EP-0174561-A1 | 7-Oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1986-03-19 | — | — | EP | claimed |
| EP-0170028-A1 | Antibacterial 7-oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1986-02-05 | — | — | EP | claimed |
| US-20240190883-A1 | KRAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-06-13 | — | — | US | disclosed |
| US-20240174643-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-05-30 | — | — | US | disclosed |
| EP-0008343-A1 | Cephalosporin derivatives, processes for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-03-05 | — | — | EP | disclosed |
| US-3965099-A | Cephalosporin esters with antibacterial activity | SMITHKLINE CORPORATION (US) | 1976-06-22 | — | — | US | disclosed |