⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861990 | 1.00 | — | — | |
| SCHEMBL3338433 | 0.78 | — | — | |
| SCHEMBL5956535 | 0.78 | — | — | |
| SCHEMBL22685410 | 0.78 | — | — | |
| SCHEMBL6536106 | 0.75 | SLC7A5 (0.36) | — | |
| SCHEMBL298986 | 0.75 | — | — | |
| SCHEMBL2027762 | 0.75 | SLC7A5 (0.36) | — | |
| SCHEMBL17222464 | 0.75 | SLC7A5 (0.36) | — | |
| SCHEMBL866414 | 0.75 | SLC7A5 (0.36) | — | |
| SCHEMBL709252 | 0.75 | SLC7A5 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131032-A1 | NEUROTHERAPEUTIC TREATMENT FOR SEXUAL DYSFUNCTION | REVAAX PHARMACEUTICALS, LLC (US) | 2013-05-23 | — | — | US | claimed |
| US-7355040-B2 | Process for the preparation of cephalosporin compounds and synthetic intermediates | ZOETIS SERVICES LLC | 2008-04-08 | — | — | US | claimed |
| EP-0725783-B1 | 2-(PYRAZOL-3-YL)CARBAPENEM DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2002-12-18 | — | — | EP | claimed |
| EP-0915843-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSES | SMITHKLINE BEECHAM PLC (GB) | 1999-05-19 | — | — | EP | claimed |
| WO-1997041098-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-11-06 | — | — | WO | claimed |
| EP-0148883-B1 | ALLOPURINOL PRODRUGS | A/S GEA Farmaceutisk Fabrik (DK) | 1990-02-14 | — | — | EP | claimed |
| US-20240115553-A1 | COMPOSITIONS AND METHODS FOR TREATING BRAIN INJURY | AZEVAN PHARMACEUTICALS, INC. (US) | 2024-04-11 | — | — | US | disclosed |
| WO-2024064209-A1 | COMPOSITIONS AND METHODS FOR TREATING MYCOBACTERIUM INFECTIONS | DATA2DISCOVERY, INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| US-20230123729-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES | AZEVAN PHARMACEUTICALS INC (US) | 2023-04-20 | — | — | US | disclosed |
| US-11628160-B2 | Compositions and methods for treating brain injury | AZEVAN PHARMACEUTICALS, INC. (US) | 2023-04-18 | — | — | US | disclosed |
| US-11319306-B2 | Compositions and methods for treating neurodegenerative diseases | AZEVAN PHARMACEUTICALS, INC. (US) | 2022-05-03 | — | — | US | disclosed |
| US-11160770-B2 | Compounds, compositions and methods for treating oxidative DNA damage disorders | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2021-11-02 | — | — | US | disclosed |
| US-20210290787-A1 | MACROCYCLE CONJUGATES | LUMIPHORE, INC. | 2021-09-23 | — | — | US | disclosed |
| US-4694006-A | Acyl- or acyloxymethyl-allopurinol prodrugs | A/S GEA (DK) | 1987-09-15 | — | — | US | disclosed |
| EP-0219926-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-04-29 | — | — | EP | disclosed |
| EP-0211656-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-02-25 | — | — | EP | disclosed |
| EP-0210815-A2 | 6-Beta-(alpha-etherified oxyimino)-acylamino penicillanic-acid derivatives, their preparation and use | BEECHAM GROUP PLC (GB) | 1987-02-04 | — | — | EP | disclosed |
| EP-0148883-A1 | ALLOPURINOL PRODRUGS. | GEA AS (DK) | 1985-07-24 | — | — | EP | disclosed |
| WO-1985000368-A1 | ALLOPURINOL PRODRUGS | A/S GEA (DK) | 1985-01-31 | — | — | WO | disclosed |
| US-3965099-A | Cephalosporin esters with antibacterial activity | SMITHKLINE CORPORATION (US) | 1976-06-22 | — | — | US | disclosed |