⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565974 | 0.81 | CES2 (0.64) | — | |
| SCHEMBL13656482 | 0.81 | CES2 (0.56) | — | |
| Ethylene SCHEMBL28075502 | 0.79 | CES2 (0.61) | — | |
| SCHEMBL31560056 | 0.79 | CES2 (0.54) | — | |
| SCHEMBL14082103 | 0.79 | — | — | |
| SCHEMBL4196929 | 0.79 | CES2 (0.61) | — | |
| SCHEMBL5873384 | 0.79 | CES2 (0.61) | — | |
| SCHEMBL24577735 | 0.78 | DAO (0.64) | — | |
| SCHEMBL25334439 | 0.78 | DAO (0.64) | — | |
| SCHEMBL9511706 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099880-A1 | Alternate Process for Remifentanil Preparation | MALLINCKRODT INC. | 2010-04-22 | — | — | US | claimed |
| EP-2125730-A2 | NEW PROCESS FOR REMIFENTANIL SYNTHESIS | Mallinckrodt Inc. (US) | 2009-12-02 | — | — | EP | claimed |
| EP-2081899-A2 | ALTERNATE PROCESS FOR REMIFENTANIL PREPARATION | Mallinckrodt Inc. (US) | 2009-07-29 | — | — | EP | claimed |
| WO-2008066708-A2 | NEW PROCESS FOR REMIFENTANIL SYNTHESIS | MALLINCKRODT INC. (US) | 2008-06-05 | — | — | WO | claimed |
| WO-2008045192-A2 | ALTERNATE PROCESS FOR REMIFENTANIL PREPARATION | MALLINCKRODT INC. (US) | 2008-04-17 | — | — | WO | claimed |
| EP-0647225-A1 | 3-ARYLURACIL DERIVATIVES AND THEIR USE AS HERBICIDES | Novartis AG (CH) | 1995-04-12 | — | — | EP | claimed |
| US-11993626-B2 | Functionalized N-acetylgalactosamine analogs | HONGENE BIOTECH CORPORATION (US) | 2024-05-28 | — | — | US | disclosed |
| US-5665746-A | BACTERICIDE | HOFFMANN-LA ROCHE INC. (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0522956-B1 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI SA (FR) | 1997-02-05 | — | — | EP | disclosed |
| US-5594135-A | BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1997-01-14 | — | — | US | disclosed |
| US-5589473-A | BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1996-12-31 | — | — | US | disclosed |
| EP-0535192-B1 | NOVEL DNA GYRASE INHIBITORS, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | HOFFMANN LA ROCHE (CH) | 1996-06-19 | — | — | EP | disclosed |
| US-5516910-A | N--2--chlorobenzyl--2--oxo and n--2--chlorobenzyl--2,2--dioxo--1,2,3--oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2--c]pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0535192-A1 | NOVEL DNA GYRASE INHIBITORS, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME. | HOFFMANN LA ROCHE (CH) | 1993-04-07 | — | — | EP | disclosed |
| US-5191090-A | Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno[3,2-c]pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |
| WO-1992018490-A1 | NOVEL DNA GYRASE INHIBITORS, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-29 | — | — | WO | disclosed |
| EP-0497695-A1 | N-2-chlorobenzyl-2-oxo and N-2-chlorobenzyl-2,2-dioxo-1,2,3-oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2-c]pyridine derivatives therefrom | SANOFI (FR) | 1992-08-05 | — | — | EP | disclosed |
| US-5068360-A | Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno(3,2-C)pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0439404-A2 | Preparation of 2-(2'-thienyl) alkylamines and derivatives thereof and synthesis of 4,5,6,7- thieno [3,2-c] pyridine derivatives therefrom | SANOFI (FR) | 1991-07-31 | — | — | EP | disclosed |