⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565974 | 0.79 | CES2 (0.64) | — | |
| SCHEMBL13656482 | 0.79 | CES2 (0.56) | — | |
| Ethylene SCHEMBL28075502 | 0.77 | CES2 (0.61) | — | |
| SCHEMBL3338643 | 0.77 | — | — | |
| SCHEMBL31560056 | 0.77 | CES2 (0.54) | — | |
| SCHEMBL5873384 | 0.77 | CES2 (0.61) | — | |
| SCHEMBL4196929 | 0.77 | CES2 (0.61) | — | |
| SCHEMBL14082103 | 0.77 | — | — | |
| SCHEMBL3338644 | 0.75 | — | — | |
| SCHEMBL18868545 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319900-B1 | FURYL, PHENYLENE AND THIENYL LEUKOTRIENE B4 ANALOGUES | G.D. Searle & Co. (US) | 1993-09-29 | — | — | EP | disclosed |
| US-4971997-A | ANTIINFLAMMATORY AGENTS, LEUKOTRIENES | G. D. SEARLE & CO. (US) | 1990-11-20 | — | — | US | disclosed |
| US-4970229-A | ANTIINFLAMMATORY AGENTS | G. D. SEARLE & CO. (US) | 1990-11-13 | — | — | US | disclosed |
| US-4970234-A | ANTIINFLAMMATORY AGENTS | G. D. SEARLE & CO. (US) | 1990-11-13 | — | — | US | disclosed |
| US-4855324-A | ANTIINFLAMMATORY AGENTS | G. D. SEARLE & CO. (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0319900-A2 | Furyl, phenylene and thienyl leukotriene B4 analogues | G.D. Searle & Co. (US) | 1989-06-14 | — | — | EP | disclosed |