Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13006928 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CACNA1H | |
| SCHEMBL6146494 | 0.75 | TSHR (0.30) | — | |
| SCHEMBL13753922 | 0.75 | ALDH1A1 (0.44) | ALDH1A1CACNA1HFPR2 | |
| 2,2,3,3-Tetramethylcyclopropanecarbonylurea SCHEMBL1577776 | 0.70 | CRBN (0.42) | ALDH1A1 | |
| SCHEMBL5675791 | 0.70 | — | — | |
| SCHEMBL14488626 | 0.68 | ALDH1A1 (0.37) | ALDH1A1CACNA1H | |
| SCHEMBL3981066 | 0.67 | POLB (0.41) | ALDH1A1FPR3FPR2 | |
| SCHEMBL3981127 | 0.67 | POLB (0.37) | ALDH1A1FPR3FPR2 | |
| SCHEMBL2939500 | 0.66 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL292864 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880157-A | ANTIEPILEPTIC AGENTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1999-03-09 | — | — | US | claimed |
| WO-1995021814-A1 | NOVEL DERIVATIVES OF TETRAMETHYLCYCLOPROPANE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1995-08-17 | — | — | WO | claimed |
| US-8846903-B2 | Acyl-urea derivatives and uses thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2014-09-30 | — | — | US | disclosed |
| US-8846903-B2 | Acyl-urea derivatives and uses thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2014-09-30 | — | — | US | disclosed |
| US-8846903-B2 | Acyl-urea derivatives and uses thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2014-09-30 | — | — | US | disclosed |
| US-8518979-B2 | Alpha-halo- and alpha-alkyl-cyclopropylcarboxy compounds and uses thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2013-08-27 | — | — | US | disclosed |
| US-20100280124-A1 | ACYL-UREA DERIVATIVES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2010-11-04 | — | — | US | disclosed |
| US-20100280124-A1 | ACYL-UREA DERIVATIVES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2010-11-04 | — | — | US | disclosed |
| US-20100280124-A1 | ACYL-UREA DERIVATIVES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2010-11-04 | — | — | US | disclosed |
| US-20100152254-A1 | ALPHA-HALO- AND ALPHA-ALKYL-CYCLOPROPYLCARBOXY COMPOUNDS AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2010-06-17 | — | — | US | disclosed |
| EP-2185505-A2 | ACYL-UREA DERIVATIVES AND USES THEREOF | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd (IL) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009001356-A2 | ACYL-UREA DERIVATIVES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009001356-A2 | ACYL-UREA DERIVATIVES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2008-12-31 | — | — | WO | disclosed |
| WO-2008102348-A1 | ALPHA-HALO- AND ALPHA-ALKYL-CYCLOPROPYLCARBOXY COMPOUNDS AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2008-08-28 | — | — | WO | disclosed |
| EP-1603891-B1 | NEW AMIDE DERIVATIVES OF 2,2,3,3-TETRAMETHYLCYCLOPROPANE CARBOXYLIC ACID | YISSUM RES DEV CO (IL) | 2008-05-28 | — | — | EP | disclosed |
| US-7232929-B2 | Amide derivatives of 2,2,3,3-tetramethylcyclopropane carboxylic acid | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2007-06-19 | — | — | US | disclosed |
| US-20060148861-A1 | Amide derivatives of 2,2,3,3-tetramethylcyclopropane carboxylic acid | YISSUM RESEARCH DEVELOPEMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-07-06 | — | — | US | disclosed |
| EP-1603891-A1 | NEW AMIDE DERIVATIVES OF 2,2,3,3-TETRAMETHYLCYCLOPROPANE CARBOXYLIC ACID | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004076432-A1 | NEW AMIDE DERIVATIVES OF 2,2,3,3-TETRAMETHYLCYCLOPROPANE CARBOXYLIC ACID | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2004-09-10 | — | — | WO | disclosed |
| US-5880157-A | ANTIEPILEPTIC AGENTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1999-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152254-A1 | ALPHA-HALO- AND ALPHA-ALKYL-CYCLOPROPYLCARBOXY COMPOUNDS AND USES THEREOF | INA, GBA1, SCN1A | ALDH1A1 865/4885CACNA1H 59/4885FPR3 4287/4885 |
| US-20060148861-A1 | Amide derivatives of 2,2,3,3-tetramethylcyclopropane carboxylic acid | CNR2, GRIN2A, GRIN2C | ALDH1A1 694/4885CACNA1H 66/4885FPR3 970/4885 |
| US-20100280124-A1 | ACYL-UREA DERIVATIVES AND USES THEREOF | ABAT, HDAC6, ACAT1 | ALDH1A1 715/4885CACNA1H 682/4885FPR3 3086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.