Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL3340420

CCCC(=O)OCC.OCCOCCO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ALDH1A1 P00352 4/20 0.46
CYP4F2 P78329 3/20 0.46
CYP4A11 Q02928 3/20 0.46
CYP1A2 P05177 1/20 0.45
MGAM O43451 1/20 0.44
GAA P10253 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
THRB P10828 1/20 0.42
HTT P42858 1/20 0.42
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
TRPA1 O75762 1/20 0.41
DGKA P23743 1/20 0.41
EPHX2 P34913 1/20 0.40
MGLL Q99685 1/20 0.40
NR1I2 O75469 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraethylene Glycol SCHEMBL3342135 0.98 MEN1 (0.45) TSHRALDH1A1CYP4F2CYP4A11CYP1A2
Triethylene Glycol SCHEMBL3339555 0.98 MEN1 (0.45) TSHRALDH1A1CYP4F2CYP4A11CYP1A2
2-Ethoxyethanol SCHEMBL8810164 0.94 ALDH1A1 (0.56) TSHRALDH1A1CYP4F2CYP4A11CYP1A2
Di(Hydroxyethyl)Ether SCHEMBL28213240 0.89 GAA (0.52) TSHRALDH1A1CYP4F2CYP4A11CYP1A2
SCHEMBL580820 0.89 ALDH1A1 (0.48) TSHRALDH1A1CYP4F2CYP4A11CYP1A2
Di(Hydroxyethyl)Ether SCHEMBL15375866 0.88 TSHR (0.54) TSHRALDH1A1CYP4F2CYP4A11CYP1A2
SCHEMBL11249003 0.88 DGKA (0.50) TSHRALDH1A1CYP4F2CYP4A11MEN1
SCHEMBL1362180 0.88 DGKA (0.50) TSHRALDH1A1CYP4F2CYP4A11MEN1
SCHEMBL28861485 0.88 DGKA (0.50) TSHRALDH1A1CYP4F2CYP4A11MEN1
SCHEMBL19666694 0.88 ALDH1A1 (0.46) TSHRALDH1A1CYP4F2CYP4A11CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4711835-A Process for photolithographing a thick layer of paste deposited on a substrate THOMSON-CSF (FR) 1987-12-08 US claimed
US-20100086788-A1 POLYVINYL ACETAL SHEET AND PROCESS FOR PRODUCTION THEREOF DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2010-04-08 US disclosed