Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LIG1 | P18858 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217934 | 0.83 | ALDH1A1 (0.43) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL262359 | 0.81 | ALDH1A1 (0.60) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3343024 | 0.78 | LIG1 (0.44) | LMNASMN1; SMN2ALDH1A1HPGDLIG1 | |
| SCHEMBL8875743 | 0.78 | GAA (0.46) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4834529 | 0.77 | BLM (0.47) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3340478 | 0.75 | TYK2 (0.51) | MAPTALDH1A1HPGDGAANPC1 | |
| SCHEMBL3224298 | 0.75 | NPC1 (0.48) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL30826239 | 0.74 | SMN1; SMN2 (0.49) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3340572 | 0.74 | ALDH1A1 (0.49) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3340569 | 0.74 | ALDH1A1 (0.49) | MEN1LMNAMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | EXELIXIS, INC. (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | S1PR1, S1PR5, S1PR3 | MEN1 525/4885LMNA 2187/4885MAPT 4318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.