Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657640 | 0.76 | NUDT1 (0.39) | NUDT1DRD1ACKR3GRM5NTRK1 | |
| SCHEMBL923355 | 0.75 | XDH (0.39) | NUDT1PIK3CGNTRK1KDM4EL3MBTL1 | |
| SCHEMBL16061763 | 0.75 | PIK3CG (0.46) | NUDT1PIK3CGNTRK1KDM4EL3MBTL1 | |
| SCHEMBL2489092 | 0.75 | NUDT1 (0.47) | NUDT1DRD1ACKR3NTRK1ALDH1A1 | |
| SCHEMBL921526 | 0.75 | CYP1A2 (0.40) | NUDT1PIK3CGNTRK1KDM4EL3MBTL1 | |
| SCHEMBL31240936 | 0.75 | NUDT1 (0.38) | NUDT1DRD1ACKR3NTRK1 | |
| SCHEMBL259658 | 0.72 | NUDT1 (0.42) | NUDT1DRD1ACKR3GRM5NTRK1 | |
| SCHEMBL3782021 | 0.71 | XDH (0.44) | NUDT1DRD1GRM5MALT1KDM4E | |
| SCHEMBL27039215 | 0.71 | PDE4B (0.33) | NUDT1PIK3CG | |
| SCHEMBL15896660 | 0.70 | NTRK1 (0.40) | NUDT1DRD1ACKR3NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | EXELIXIS, INC. (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | S1PR1, S1PR5, S1PR3 | NUDT1 1635/4885DRD1 1220/4885PIK3CG 812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.