Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL641496 | 0.99 | KMT2A (0.47) | KMT2AMEN1HCRTR1HCRTR2BDKRB1 | |
| SCHEMBL641485 | 0.92 | MEN1 (0.47) | KMT2AMEN1HCRTR1HCRTR2BDKRB1 | |
| SCHEMBL10205740 | 0.79 | KMT2A (0.55) | KMT2AMEN1HCRTR1HCRTR2BDKRB1 | |
| SCHEMBL15204129 | 0.78 | BDKRB1 (0.45) | KMT2AMEN1HCRTR1HCRTR2BDKRB1 | |
| SCHEMBL13692072 | 0.78 | PSEN1 (0.59) | KMT2AMEN1HCRTR1HCRTR2BDKRB1 | |
| Hydrochloric Acid SCHEMBL2570810 | 0.78 | BDKRB1 (0.44) | KMT2AMEN1HCRTR1HCRTR2BDKRB1 | |
| SCHEMBL640634 | 0.78 | HTR7 (0.40) | KMT2AMEN1TP53TSHRALDH1A1 | |
| SCHEMBL640635 | 0.78 | HTR7 (0.40) | KMT2AMEN1TP53TSHRALDH1A1 | |
| SCHEMBL639411 | 0.77 | HTR7 (0.39) | KMT2AMEN1TP53TSHRALDH1A1 | |
| SCHEMBL639412 | 0.77 | HTR7 (0.39) | KMT2AMEN1TP53TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152158-A1 | Substituted Disulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-06-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152158-A1 | Substituted Disulfonamide Compounds | BDKRB1, BDKRB2, BRS3 | KMT2A 2575/4885MEN1 1203/4885HCRTR1 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.