Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 19/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL2398321 | 0.92 | ACHE (0.67) | ACHE | |
| Fumaric Acid SCHEMBL23668767 | 0.92 | ACHE (0.67) | ACHE | |
| SCHEMBL6262731 | 0.81 | ACHE (0.68) | ACHE | |
| Zanapezil SCHEMBL678642 | 0.81 | ACHE (1.00) | ACHE | |
| Zanapezil SCHEMBL29366424 | 0.81 | ACHE (1.00) | ACHE | |
| SCHEMBL7850897 | 0.80 | ACHE (0.63) | ACHE | |
| SCHEMBL9204959 | 0.80 | ACHE (1.00) | ACHE | |
| Hydrochloric Acid SCHEMBL7846894 | 0.80 | ACHE (0.62) | ACHE | |
| Hydrochloric Acid SCHEMBL7848461 | 0.80 | ACHE (0.59) | ACHE | |
| SCHEMBL5636671 | 0.78 | ACHE (0.75) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152164-A1 | Method For Stabilizing Anti-Dementia Drug | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-06-17 | — | — | US | claimed |
| US-20080213368-A1 | Method for Stabilizing Anti-Dementia Drug | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-09-04 | — | — | US | claimed |
| EP-1830886-A1 | METHOD FOR STABILIZING ANTI-DEMENTIA DRUG | Eisai R&D Management Co., Ltd. (JP) | 2007-09-12 | — | — | EP | claimed |
| WO-2006070930-A1 | METHOD FOR STABILIZING ANTI-DEMENTIA DRUG | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2006-07-06 | — | — | WO | claimed |
| EP-2892514-A1 | ANTICHOLINERGIC NEUROPROTECTIVE COMPOSITION AND METHODS | Chase Pharmaceuticals Corporation (US) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014039627-A1 | ANTICHOLINERGIC NEUROPROTECTIVE COMPOSITION AND METHODS | CHASE PHARMACEUTICALS CORPORATION (US) | 2014-03-13 | — | — | WO | disclosed |
| US-8507527-B2 | Method for stabilizing anti-dementia drug | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8481565-B2 | Rivastigmine, galantamine, donepezil; ethylcellulose high molecular weight basic water-insoluble polymer; methacrylic acid-ethyl acrylate high molecular weight acidic enteric polymer; succinic acid, ascorbic acid low molecular weight anti-oxidant; sustained-release base prevent, inhibit degradation | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-07-09 | — | — | US | disclosed |
| US-20100152164-A1 | Method For Stabilizing Anti-Dementia Drug | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20080213368-A1 | Method for Stabilizing Anti-Dementia Drug | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-09-04 | — | — | US | disclosed |
| EP-1830886-A1 | METHOD FOR STABILIZING ANTI-DEMENTIA DRUG | Eisai R&D Management Co., Ltd. (JP) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006070930-A1 | METHOD FOR STABILIZING ANTI-DEMENTIA DRUG | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2006-07-06 | — | — | WO | disclosed |
| US-20060003989-A1 | Compositions and methods using acetylcholinesterase (ACE) inhibitors to treat central nervous system (CNS) disorders in mammals | NASTECH PHARMACEUTICAL COMPANY INC. | 2006-01-05 | — | — | US | disclosed |
| US-20030225031-A1 | Administration of acetylcholinesterase inhibitors to the cerebral spinal fluid | NASTECH PHARMACEUTICAL COMPANY INC. | 2003-12-04 | — | — | US | disclosed |