Protirelin

Protirelin

SCHEMBL33419

NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

TRHR

The experimentally established mechanism targets of Protirelin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRHR known ✓ P34981 6/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Protirelin SCHEMBL10087855 1.00 TRHR (1.00) TRHR
Protirelin SCHEMBL10087946 1.00 TRHR (1.00) TRHR
Protirelin SCHEMBL16091769 1.00 TRHR (1.00) TRHR
Protirelin SCHEMBL4406163 0.97 TRHR (0.93) TRHR
Protirelin SCHEMBL1007386 0.95 TRHR (0.91) TRHR
SCHEMBL29539733 0.92 TRHR (0.85) TRHR
Azetirelin SCHEMBL195158 0.92 TRHR (0.85) TRHR
Protirelin SCHEMBL11309963 0.92 TRHR (0.84) TRHR
SCHEMBL16072685 0.91 TRHR (0.84) TRHR
SCHEMBL16088505 0.91 TRHR (0.84) TRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11876 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY BHAMIS RES LABORATORY PVT LTD (IN) 2026-05-07 US claimed
US-12533321-B2 Polypeptide formulations for oral delivery Bhami's Research Laboratory, Pvt. Ltd. (IN) 2026-01-27 US claimed
EP-4631514-A1 ORAL POLYPEPTIDE COMPOSITION AND USE THEREOF Hefei Tianhui Biotech Co., Ltd. (CN) 2025-10-15 EP claimed
EP-4601623-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2025-08-20 EP claimed
WO-2025118074-A1 OLFACTORY DELIVERY OF THERAPEUTIC PEPTIDES ROCKET SCIENCE HEALTH CORP. (CA) 2025-06-12 WO claimed
EP-3661539-B1 OPTIMIZED PEPTIDES FOR TARGETING HUMAN NERVES AND THEIR USE IN IMAGE GUIDED SURGERY, DIAGNOSTICS AND THERAPEUTIC DELIVERY UNIV CALIFORNIA (US) 2024-10-09 EP claimed
EP-2964658-B1 POSITRON-EMITTING SUBSTITUTED ORGANOFLUOROBORATES AS IMAGING AGENTS UNIV BRITISH COLUMBIA (CA) 2024-08-07 EP claimed
WO-2024133655-A1 PEST CONTROL COMPOSITION Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2024-06-27 WO claimed
CN-117899200-A Medicament for enhancing curative effect of immunotherapy and application of medicament in treating tumors 华中科技大学 2024-04-19 CN claimed
US-20240122860-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 US claimed
WO-1988000837-A2 ADVANCED ANTICANCER THERAPY AND CYTOTOXIC MEDICAMENTS FOR ITS IMPLEMENTATION BATTELLE MEMORIAL INSTITUTE (CH) 1988-02-11 WO claimed
US-4707454-A Fluorescent chlorophyll labeled assay reagents BIO-DIAGNOSTICS, INC. (US) 1987-11-17 US claimed
US-4670419-A POLYPEPTIDE AND CYCLODEXTRIN TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-06-02 US claimed
US-4659696-A MIXTURE OF POLYPEPTIDE AND CYCLODEXTRIN TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-04-21 US claimed
EP-0071991-B1 IMPROVED FLUORO IMMUNO ASSAY SYSTEM BIO-DIAGNOSTICS, INC. (US) 1986-05-14 EP claimed
US-4426378-A Thyrotropin releasing hormone in therapy of shock and as a central nervous system stimulant THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1984-01-17 US claimed
US-4374828-A PEPTIDES, IMMUNE SYSTEM ENHANCEMENT BOARD OF REAGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1983-02-22 US claimed
EP-0071991-A2 Improved fluoro immuno assay system BIO-DIAGNOSTICS, INC. (US) 1983-02-16 EP claimed
US-4045556-A ANTIDEPRESSANTS, PYSCHOSTIMULANTS; SILYLATION SCHWERTNER EBERHARD 1977-08-30 US claimed
US-3988307-A ATTACHING AN ALPHA,BETA-UNSATURATED AMINO ACID TO A SOLID SUPPORT; ACIDIC AQUEOUS RELEASE AGENT THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1976-10-26 US claimed