Methacrylic Acid

Methacrylic Acid

SCHEMBL3342142

C=C(C)C(=O)O.C=C(C)C(=O)O[SiH](C)C

nearest known ligand 0.44

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 3/20 0.35
THRB P10828 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
ELANE P08246 1/20 0.32
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6137384 0.93
Methacrylic Acid SCHEMBL28680050 0.77 ALDH1A1 (0.38) ALDH1A1TSHRTDP1
SCHEMBL21065526 0.76
Methacrylic Acid SCHEMBL28776399 0.76 TDP1 (0.44) ALDH1A1TSHRTDP1
Methacrylic Acid SCHEMBL1930983 0.76 TDP1 (0.44) ALDH1A1TSHRTDP1
Methacrylic Acid SCHEMBL820485 0.76
Methacrylic Acid SCHEMBL3360715 0.75 ALDH1A1 (0.36) ALDH1A1TDP1
Methacrylic Acid SCHEMBL440900 0.75 ALDH1A1 (0.36) ALDH1A1TDP1
SCHEMBL10897664 0.75
Methacrylic Acid SCHEMBL4305464 0.74 ALDH1A1 (0.52) ALDH1A1TSHRTHRBTDP1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273910-B2 Process for silylating monocarboxylic acids BASF SE (DE) 2012-09-25 US disclosed
US-20100152472-A1 PROCESS FOR SILYLATING MONOCARBOXYLIC ACIDS BASF SE (DE) 2010-06-17 US disclosed