Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3341802 | 0.87 | TSHR (0.49) | TSHRCYP3A4MAPTNPSR1KDM4E | |
| 4-Nitroquinoline-1-Oxide SCHEMBL105454 | 0.76 | MAPT (0.56) | TSHRCYP3A4MAPTNPSR1KDM4E | |
| 4-Nitroquinoline-1-Oxide SCHEMBL29367999 | 0.76 | MAPT (0.56) | TSHRCYP3A4MAPTNPSR1KDM4E | |
| 4-Nitroquinoline-1-Oxide SCHEMBL21114410 | 0.76 | MAPT (0.56) | TSHRCYP3A4MAPTNPSR1KDM4E | |
| 4-Nitroquinoline-1-Oxide SCHEMBL140249 | 0.73 | MAPT (0.51) | TSHRCYP3A4MAPTNPSR1KDM4E | |
| SCHEMBL5803068 | 0.71 | MAPT (0.43) | MAPTNPSR1KDM4ENPC1S1PR4 | |
| SCHEMBL1561998 | 0.69 | TSHR (0.60) | TSHRCYP3A4MAPTNPSR1MITF | |
| SCHEMBL2511534 | 0.68 | TDP1 (0.52) | TSHRCYP3A4MAPTNPSR1KDM4E | |
| SCHEMBL29440728 | 0.68 | TDP1 (0.52) | TSHRCYP3A4MAPTNPSR1KDM4E | |
| SCHEMBL539611 | 0.68 | TDP1 (0.52) | TSHRCYP3A4MAPTNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |