Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CTSB | P07858 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Nitroquinoline-1-Oxide SCHEMBL21114410 | 1.00 | MAPT (0.56) | MAPTMITFKDM4ENPC1S1PR4 | |
| 4-Nitroquinoline-1-Oxide SCHEMBL29367999 | 1.00 | MAPT (0.56) | MAPTMITFKDM4ENPC1S1PR4 | |
| 4-Nitroquinoline-1-Oxide SCHEMBL140249 | 0.92 | MAPT (0.51) | MAPTMITFKDM4ENPC1S1PR4 | |
| SCHEMBL2796338 | 0.87 | TDP1 (0.59) | MAPTMITFKDM4ENPC1S1PR4 | |
| 4-Nitroquinoline-1-Oxide SCHEMBL9510491 | 0.82 | MAPT (0.46) | MAPTMITFKDM4ENPC1S1PR4 | |
| SCHEMBL16704752 | 0.80 | MAPT (0.53) | MAPTMITFKDM4ENPC1S1PR4 | |
| SCHEMBL7464842 | 0.76 | MAPT (0.48) | MAPTMITFKDM4ENPC1S1PR4 | |
| SCHEMBL3341802 | 0.76 | TSHR (0.49) | MAPTMITFKDM4ENPC1S1PR4 | |
| SCHEMBL5803068 | 0.76 | MAPT (0.43) | MAPTMITFKDM4ENPC1S1PR4 | |
| SCHEMBL3342386 | 0.76 | TSHR (0.49) | MAPTMITFKDM4ENPC1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1995 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139331-A1 | HIGH-THROUGHPUT METHODS FOR ISOLATING AND CHARACTERIZING AMMONIUM-EXCRETING MUTANT LIBRARIES GENERATED BY CHEMICAL MUTAGENESIS | PIVOT BIO INC (US) | 2026-05-21 | — | — | US | claimed |
| EP-4496889-A1 | METHOD FOR DETECTING THE MUTAGENIC CHARACTER OF CHEMICAL COMPOUNDS | Genevolution (FR) | 2025-01-29 | — | — | EP | claimed |
| US-20240271119-A1 | METHODS OF PERIPLASMIC PHAGE-ASSISTED CONTINUOUS EVOLUTION | THE BROAD INSTITUTE, INC. (US) | 2024-08-15 | — | — | US | claimed |
| EP-4377455-A1 | METHODS OF PERIPLASMIC PHAGE-ASSISTED CONTINUOUS EVOLUTION | The Broad Institute Inc. (US) | 2024-06-05 | — | — | EP | claimed |
| EP-4376823-A1 | COMPOUNDS INHIBITING THE SYNERGISTIC CARSINOGENIC EFFECT OF HEAVY METALS IN THE PRESENCE OF OTHER CARCINOGENS FOR USE IN THE TREATMENT OF CANCER | Cancer Research And Biotechnology Ag (CH) | 2024-06-05 | — | — | EP | claimed |
| US-20240174860-A1 | HIGH OLEIC OIL COMPOSITIONS AND USES THEREOF | CHECKERSPOT, INC. | 2024-05-30 | — | — | US | claimed |
| CN-117886916-A | N227 locus glycosylation of SBSPON and application thereof in bladder cancer drug resistance | 深圳市第二人民医院(深圳市转化医学研究院) | 2024-04-16 | — | — | CN | claimed |
| CN-117169522-A | Mass spectrum positive ion mode metabonomics biomarker for peri-implant inflammation and application thereof | 暨南大学附属第一医院（广州华侨医院） | 2023-12-05 | — | — | CN | claimed |
| CN-117025513-A | Preparation method of esophageal organoid cancerous tissue | 上海市东方医院（同济大学附属东方医院） | 2023-11-10 | — | — | CN | claimed |
| WO-2023180209-A1 | METHOD FOR DETECTING THE MUTAGENIC CHARACTER OF CHEMICAL COMPOUNDS | GENEVOLUTION (FR) | 2023-09-28 | — | — | WO | claimed |
| EP-0576622-B1 | LITHOGRAPHIC PRINTING PLATES | EASTMAN KODAK CO (US) | 1997-11-05 | — | — | EP | claimed |
| EP-0576622-A1 | LITHOGRAPHIC PRINTING PLATES | EASTMAN KODAK COMPANY (US) | 1994-01-05 | — | — | EP | claimed |
| WO-1992017821-A1 | LITHOGRAPHIC PRINTING PLATES | EASTMAN KODAK COMPANY (US) | 1992-10-15 | — | — | WO | claimed |
| US-5141842-A | Negative working lithography printing plates | EASTMAN KODAK COMPANY (US) | 1992-08-25 | — | — | US | claimed |
| US-5141839-A | LITHOGRAPHIC PRINTING PLATES HAVING A RADIATION-SENSITIVE LAYER COMPRISING A PHOTOCROSSLINKABLE POLYMER, A LEUCO DYE, A PHOTOOXIDANT AND A HETEROAROMATIC AMINE N-OXIDE | EASTMAN KODAK COMPANY (US) | 1992-08-25 | — | — | US | claimed |
| US-5100768-A | Photoresists for integrated circuits, polyvinyl phenol and nitrogen containing heterocycle | KABUSHIKI KAISHA TOSHIBA (JP) | 1992-03-31 | — | — | US | claimed |
| EP-0449820-A1 | RADIATION/MICROBE BIOASSAY | TECHNICAL ASSESSMENT SYSTEMS, INC. (US) | 1991-10-09 | — | — | EP | claimed |
| EP-0397474-A2 | Photosensitive composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1990-11-14 | — | — | EP | claimed |
| WO-1989010549-A2 | RADIATION/MICROBE BIOASSAY | TECHNICAL ASSESSMENT SYSTEMS, INC. (US) | 1989-11-02 | — | — | WO | claimed |
| US-4568628-A | Water developable diazo printing plate composition with quaternary nitrogen stabilizer | POLYCHROME CORPORATION (US) | 1986-02-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260139331-A1 | HIGH-THROUGHPUT METHODS FOR ISOLATING AND CHARACTERIZING AMMONIUM-EXCRETING MUTANT LIBRARIES GENERATED BY CHEMICAL MUTAGENESIS | GLUL, SPOUT1, QPCTL | MAPT 3334/4885MITF 1565/4885KDM4E 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.