Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL539611 | 0.84 | TDP1 (0.52) | TDP1TSHRSMN1; SMN2HSD17B10CYP3A4 | |
| SCHEMBL29440728 | 0.84 | TDP1 (0.52) | TDP1TSHRSMN1; SMN2HSD17B10CYP3A4 | |
| SCHEMBL27331521 | 0.81 | TDP1 (0.48) | TDP1TSHRSMN1; SMN2HSD17B10CYP3A4 | |
| SCHEMBL21644467 | 0.81 | TDP1 (0.48) | TDP1TSHRSMN1; SMN2HSD17B10CYP3A4 | |
| SCHEMBL28224311 | 0.81 | TDP1 (0.48) | TDP1TSHRSMN1; SMN2HSD17B10CYP3A4 | |
| SCHEMBL9784653 | 0.77 | TDP1 (0.44) | TDP1TSHRSMN1; SMN2HSD17B10CYP3A4 | |
| SCHEMBL26104895 | 0.74 | TSHR (0.44) | TDP1TSHRSMN1; SMN2HSD17B10CYP3A4 | |
| SCHEMBL192328 | 0.73 | TDP1 (0.46) | TDP1TSHRSMN1; SMN2HSD17B10CYP3A4 | |
| SCHEMBL31329852 | 0.73 | CYP1A2 (0.42) | TDP1TSHRSMN1; SMN2HSD17B10CYP3A4 | |
| SCHEMBL27875406 | 0.73 | CYP1A2 (0.42) | TDP1TSHRSMN1; SMN2HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034947-B2 | Pyridine oxide compound, and process for producing carboxylic acid derivative and optically active carboxylic acid derivative with the use of the same | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2011-10-11 | — | — | US | disclosed |
| US-20090062548-A1 | NOVEL PYRIDINE OXIDE COMPOUND, AND PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE AND OPTICALLY ACTIVE CARBOXYLIC ACID DERIVATIVE WITH THE USE OF THE SAME | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062548-A1 | NOVEL PYRIDINE OXIDE COMPOUND, AND PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE AND OPTICALLY ACTIVE CARBOXYLIC ACID DERIVATIVE WITH THE USE OF THE SAME | ADH5, ADH1A, ADH1C | TDP1 4686/4885TSHR 1067/4885SMN1; SMN2 4511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.