SCHEMBL3342426

SCHEMBL3342426

O=[N+]([O-])C1=CC=C(O)C(=NCc2ccccn2)C1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.38
KMT2A Q03164 3/20 0.38
ALDH1A1 P00352 3/20 0.37
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 1/20 0.37
POLB P06746 1/20 0.36
MGMT P16455 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
MAP1LC3B Q9GZQ8 1/20 0.33
TLR4 O00206 1/20 0.33
TLR2 O60603 1/20 0.33
CTSB P07858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3347650 0.88 POLB (0.39) L3MBTL1KMT2AALDH1A1NPC1RAB9A
SCHEMBL3845804 0.81 PTPRA (0.39) L3MBTL1KMT2AALDH1A1NPC1RAB9A
SCHEMBL3342831 0.78 SMN1; SMN2 (0.38) L3MBTL1KMT2AALDH1A1NPC1RAB9A
SCHEMBL3347444 0.76 MAP1LC3B (0.37) L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL3341800 0.75 PDE4D (0.33) KMT2AALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL3342443 0.75 ALDH1A1 (0.36) L3MBTL1KMT2AALDH1A1NPC1RAB9A
SCHEMBL3844212 0.75 TP53 (0.34) ALDH1A1KDM4E
SCHEMBL3341792 0.71 SMN1; SMN2 (0.41) L3MBTL1KMT2AALDH1A1NPC1RAB9A
SCHEMBL3347065 0.64 SMN1; SMN2 (0.40) L3MBTL1KMT2AALDH1A1NPC1RAB9A
SCHEMBL3342423 0.63 KMT2A (0.35) L3MBTL1KMT2AALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2010550-B1 POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES TOTAL RES & TECHNOLOGY FELUY (BE) 2013-06-19 EP disclosed
US-8399582-B2 Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-03-19 US disclosed
US-20100160583-A1 Polymerisation of Ethylene and Alpha-Olefins with Pyridino-Iminophenol Complexes TOTAL PETROCHEMICALS RESEARCH FEULY (BE) 2010-06-24 US disclosed
EP-1849791-A1 Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2007-10-31 EP disclosed