SCHEMBL3342564

SCHEMBL3342564

C=CCc1cc(S(=O)(=O)c2ccc(O)cc2)ccc1O

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.88
GABRA1 P14867 2/20 0.53
GABRB2 P47870 2/20 0.53
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
HPGD P15428 1/20 0.45
HTT P42858 1/20 0.45
GAA P10253 3/20 0.43
MAPT P10636 2/20 0.43
MEN1 O00255 1/20 0.43
ALOX5 P09917 1/20 0.43
GABRB1 P18505 1/20 0.43
RXRA P19793 1/20 0.43
CNR1 P21554 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43
CNR2 P34972 1/20 0.43
GABRA2 P47869 1/20 0.43
KMT2A Q03164 1/20 0.43
ACE2 Q9BYF1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28231 0.94 POLB (1.00) POLBGABRA1GABRB2ALDH1A1LMNA
SCHEMBL29375900 0.94 POLB (1.00) POLBGABRA1GABRB2ALDH1A1LMNA
SCHEMBL29420401 0.94 POLB (1.00) POLBGABRA1GABRB2ALDH1A1LMNA
SCHEMBL3403169 0.94 POLB (1.00) POLBGABRA1GABRB2ALDH1A1LMNA
SCHEMBL13356448 0.88 POLB (0.88) POLBGABRA1GABRB2ALDH1A1LMNA
SCHEMBL15998571 0.84 POLB (0.76) POLBGABRA1GABRB2ALDH1A1LMNA
SCHEMBL5879420 0.83 POLB (0.74) POLBGABRA1GABRB2ALDH1A1LMNA
SCHEMBL3342563 0.83 POLB (0.74) POLBGABRA1GABRB2ALDH1A1LMNA
SCHEMBL7331957 0.82 POLB (0.78) POLBGABRA1GABRB2ALDH1A1LMNA
SCHEMBL8570848 0.82 POLB (0.59) POLBALDH1A1GAAMAPTCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0913267-B1 THERMAL RECORDING MATERIAL AND NOVEL CRYSTAL OF BISPHENOL S DERIVATIVE NIPPON KAYAKU KK (JP) 2004-01-21 EP claimed
US-6114282-A CRYSTALS OF 3,3'-DIALLYL-4,4'-DIHYDROXYDIPHENYL SULFONEDEVELOPER NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2000-09-05 US claimed
EP-0913267-A1 THERMAL RECORDING MATERIAL AND NOVEL CRYSTAL OF BISPHENOL S DERIVATIVE Nippon Kayaku Kabushiki Kaisha (JP) 1999-05-06 EP claimed
US-4880767-A COLOR FORMING SYSTEMS, FLUORENE DYES, DYE DEVELOPERS MITSUBISHI PAPER MILLS (JP) 1989-11-14 US claimed
US-4874740-A ARYL DIESTERS,DIETHERS AND DIHYDROXYARYL SULFONES; SENSITIZERS AND DEVELOPERS; COLOR DEVELOPMENT BY HEATING MITSUBISHI PAPER MILLS, LTD. (JP) 1989-10-17 US claimed
US-4742042-A Thermosensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1988-05-03 US claimed
JP-11198545-A None JP disclosed
JP-11208122-A None JP disclosed
JP-11208121-A None JP disclosed
US-10899153-B2 Heat-sensitive recording material and diphenylsulfone NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2021-01-26 US disclosed
US-20180312465-A1 Heat-Sensitive Recording Material And Diphenylsulfone NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-11-01 US disclosed
EP-3378666-A1 HEAT-SENSITIVE RECORDING MATERIAL AND DIPHENYLSULFONE Nippon Kayaku Kabushiki Kaisha (JP) 2018-09-26 EP disclosed
US-8283286-B2 Thermosensitive recording material NICCA CHEMICAL CO., LTD. (JP) 2012-10-09 US disclosed
JP-H11208121-A THERMAL RECORDING BODY OJI PAPER CO LTD 1999-08-03 JP disclosed
JP-H11198545-A THERMAL RECORDING MATERIAL OJI PAPER CO LTD 1999-07-27 JP disclosed
EP-0913267-A1 THERMAL RECORDING MATERIAL AND NOVEL CRYSTAL OF BISPHENOL S DERIVATIVE Nippon Kayaku Kabushiki Kaisha (JP) 1999-05-06 EP disclosed
US-4983569-A Color-forming layer comprising a fluorene dye chromogen, a developer, an isocyanate and an imino compound; infrared absorption; storage stability; colorfastness MITSUBISHI PAPER MILLS (JP) 1991-01-08 US disclosed
US-4880767-A COLOR FORMING SYSTEMS, FLUORENE DYES, DYE DEVELOPERS MITSUBISHI PAPER MILLS (JP) 1989-11-14 US disclosed
US-4874740-A ARYL DIESTERS,DIETHERS AND DIHYDROXYARYL SULFONES; SENSITIZERS AND DEVELOPERS; COLOR DEVELOPMENT BY HEATING MITSUBISHI PAPER MILLS, LTD. (JP) 1989-10-17 US disclosed
US-4742042-A Thermosensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1988-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180312465-A1 Heat-Sensitive Recording Material And Diphenylsulfone HSPA4L, WFS1, HSPH1 POLB 1046/4885GABRA1 4191/4885GABRB2 4261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.