SCHEMBL3342849

SCHEMBL3342849

CN(C(=O)c1cnc(OC2CCN(C(=O)OC(C)(C)C)CC2)cn1)c1ccc(S(C)(=O)=O)nc1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3343204 0.84 GPR119 (0.55) GPR119
SCHEMBL2548178 0.79 GPR119 (1.00) GPR119
SCHEMBL12283497 0.79 GPR119 (1.00) GPR119
SCHEMBL3342841 0.77 GPR119 (0.60) GPR119
SCHEMBL3344956 0.76 GPR119 (0.64) GPR119
SCHEMBL3342822 0.75 GPR119 (0.61) GPR119
SCHEMBL23311669 0.73 GPR119 (0.67) GPR119
SCHEMBL20137797 0.73 GPR119 (0.67) GPR119
SCHEMBL14634550 0.72 GPR119 (0.81) GPR119
SCHEMBL14634551 0.72 GPR119 (0.81) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010048149-A2 HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE KALYPSYS, INC. (US) 2010-04-29 WO disclosed