SCHEMBL3343056

SCHEMBL3343056

C=CC(=O)NCCP(=O)(OCC)OCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.47
PPARD Q03181 2/20 0.46
TSHR P16473 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPK1 P28482 1/20 0.45
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
FPR2 P25090 1/20 0.37
BTK Q06187 2/20 0.33
PLAU P00749 1/20 0.33
GAA P10253 2/20 0.33
TGM2 P21980 1/20 0.33
MEN1 O00255 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491502 0.90 ZDHHC20 (0.53) ZDHHC20ZDHHC2PPARDTSHRTDP1
SCHEMBL23558786 0.82 PPARD (0.37) ZDHHC20ZDHHC2PPARDTSHRTDP1
SCHEMBL491449 0.82 TSHR (0.43) ZDHHC20ZDHHC2PPARDTSHRTDP1
SCHEMBL7741589 0.81 ZDHHC20 (0.44) ZDHHC20ZDHHC2PPARDTSHRTDP1
SCHEMBL8920004 0.78 PPARD (0.52) PPARDTSHRALDH1A1MAPK1CA12
SCHEMBL787330 0.77 PPARD (0.50) PPARDTSHRCA12CA1CA2
SCHEMBL3345630 0.76 PPARD (0.46) PPARDTSHRTDP1MAPK1CA12
SCHEMBL3345153 0.75 TAS1R3 (0.42) ZDHHC20ZDHHC2PPARDTSHRTDP1
SCHEMBL3147522 0.75 PPARD (0.48) PPARDTSHRTDP1ALDH1A1CA12
SCHEMBL491800 0.75 PPARD (0.62) PPARDTSHRTDP1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170218099-A1 POLYPHOSPHORUS POLYMER THAT IS THIOL-FUNCTIONALISED AT THE CHAIN ENDS AND PRODUCTION METHOD THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-08-03 US claimed
WO-2015121228-A1 PHOSPHORUS DIENE BLOCK COPOLYMER, METHOD FOR THE SYNTHESIS THEREOF AND RUBBER COMPOSITION CONTAINING SAME COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-08-20 WO claimed
US-20170218099-A1 POLYPHOSPHORUS POLYMER THAT IS THIOL-FUNCTIONALISED AT THE CHAIN ENDS AND PRODUCTION METHOD THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-08-03 US disclosed
US-20170022296-A1 METHOD FOR PRODUCING DIENE POLYMERS BEARING PHOSPHORUS FUNCTIONAL GROUPS, PRODUCTS RESULTING FROM SAID METHOD AND COMPOSITION CONTAINING SAME COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-01-26 US disclosed
EP-3105260-A1 POLYPHOSPHORUS POLYMER THAT IS THIOL-FUNCTIONALISED AT THE CHAIN ENDS AND PRODUCTION METHOD THEREOF Compagnie Générale des Etablissements Michelin (FR) 2016-12-21 EP disclosed
WO-2015199555-A1 POLYMERS FOR COATING NANOPARTICLES NAYSMITH BRIAR (NZ) 2015-12-30 WO disclosed
WO-2015121225-A1 POLYMER BEARING PHOSPHORUS FUNCTIONAL GROUPS AND AT LEAST ONE AZIDE FUNCTIONAL GROUP, METHOD FOR THE SYNTHESIS THEREOF AND USE OF SAME COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-08-20 WO disclosed
WO-2015121228-A1 PHOSPHORUS DIENE BLOCK COPOLYMER, METHOD FOR THE SYNTHESIS THEREOF AND RUBBER COMPOSITION CONTAINING SAME COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-08-20 WO disclosed
WO-2015121223-A1 POLYPHOSPHORUS POLYMER THAT IS THIOL-FUNCTIONALISED AT THE CHAIN ENDS AND PRODUCTION METHOD THEREOF COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-08-20 WO disclosed
US-8105689-B2 Adhesive, coating or film composition applied to a surface BASF SE (DE) 2012-01-31 US disclosed
US-8105689-B2 Adhesive, coating or film composition applied to a surface BASF SE (DE) 2012-01-31 US disclosed
US-20100160485-A1 Hydrolysis stable self-etching, self-priming adhesive KLEE JOACHIM 2010-06-24 US disclosed
US-20080194730-A1 Hydrolysis stable self-etching, self-priming adhesive KLEE JOACHIM 2008-08-14 US disclosed
US-20070028805-A1 (Meth)acrylamide phosphorus monomer compositions BASF SE (DE) 2007-02-08 US disclosed
US-20070028805-A1 (Meth)acrylamide phosphorus monomer compositions BASF SE (DE) 2007-02-08 US disclosed
WO-2007006648-A1 (METH)ACRYLAMIDE PHOSPHORUS MONOMER COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-01-18 WO disclosed
EP-1437999-B1 HYDROLYSIS STABLE SELF-ETCHING, SELF-PRIMING ADHESIVE DENTSPLY DETREY GMBH (DE) 2006-12-20 EP disclosed
US-20040266906-A1 Hydrolysis stable self-etching,self-priming adhesive KLEE JOACHIM (DE) 2004-12-30 US disclosed
EP-1437999-A1 HYDROLYSIS STABLE SELF-ETCHING, SELF-PRIMING ADHESIVE DENTSPLY DETREY GmbH (DE) 2004-07-21 EP disclosed
WO-2003035013-A1 HYDROLYSIS STABLE SELF-ETCHING, SELF-PRIMING ADHESIVE DENTSPLY DETREY GMBH (DE) 2003-05-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194730-A1 Hydrolysis stable self-etching, self-priming adhesive PPA1, PHOSPHO1, PDAP1 ZDHHC20 4120/4885ZDHHC2 4146/4885PPARD 3115/4885
US-20100160485-A1 Hydrolysis stable self-etching, self-priming adhesive PPA1, PHOSPHO1, PDAP1 ZDHHC20 4120/4885ZDHHC2 4146/4885PPARD 3115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.