SCHEMBL334325

SCHEMBL334325

CCCCCCCC(=S)OCCC[Si](OC)(OC)OC

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA9 Q16790 3/20 0.41
DGKA P23743 1/20 0.38
LPAR2 Q9HBW0 6/20 0.34
LPAR3 Q9UBY5 6/20 0.34
NAAA Q02083 1/20 0.34
ENPP2 Q13822 4/20 0.33
LPAR6 P43657 3/20 0.33
LPAR1 Q92633 3/20 0.33
LPAR4 Q99677 3/20 0.33
LPAR5 Q9H1C0 3/20 0.33
DNM1 Q05193 1/20 0.33
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5088570 0.85 CA12 (0.40) CA12CA1CA2CA9DGKA
SCHEMBL1535742 0.85 CA12 (0.40) CA12CA1CA2CA9DGKA
SCHEMBL1535815 0.85 CA12 (0.40) CA12CA1CA2CA9DGKA
SCHEMBL333445 0.85 CA12 (0.40) CA12CA1CA2CA9DGKA
SCHEMBL1535780 0.85 CA12 (0.40) CA12CA1CA2CA9DGKA
SCHEMBL5090625 0.85 CA12 (0.40) CA12CA1CA2CA9DGKA
SCHEMBL12080514 0.83 CA12 (0.39) CA12CA1CA2CA9DGKA
SCHEMBL11660351 0.82 CA12 (0.57) CA12CA1CA2CA9DGKA
SCHEMBL22612261 0.82 CA12 (0.57) CA12CA1CA2CA9DGKA
SCHEMBL22612322 0.82 CA12 (0.52) CA12CA1CA2CA9DGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220363873-A1 SILANE COUPLING AGENT COMPOSITION COMPRISING SILANE COMPOUND AND PROTEIN MODIFYING AGENT, AND RUBBER COMPOSITION COMPRISING THE SAME ENEOS CORPORATION (JP) 2022-11-17 US claimed
EP-3981610-A1 SILANE COUPLING AGENT COMPOSITION CONTAINING SILANE COMPOUND AND PROTEIN DENATURING AGENT, AND RUBBER COMPOSITION CONTAINING SAID COMPOSITION ENEOS Corporation (JP) 2022-04-13 EP claimed
CN-113795499-A Process for producing alkoxysilyl group-containing thiocarboxylic ester 迈图高新材料公司 2021-12-14 CN claimed
US-10919920-B2 Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2021-02-16 US claimed
US-20200347084-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS MOMENTIVE PERFORMANCE MATERIALS INC. 2020-11-05 US claimed
EP-2978768-B1 CATALYTIC PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE MOMENTIVE PERFORMANCE MAT INC (US) 2017-11-29 EP claimed
EP-2978768-A1 CATALYTIC PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE Momentive Performance Materials Inc. (US) 2016-02-03 EP claimed
EP-1560836-B1 PROCESS FOR MANUFACTURE OF BLOCKED MERCAPTOSILANE COUPLING AGENTS MOMENTIVE PERFORMANCE MAT INC (US) 2015-12-30 EP claimed
US-9206203-B2 Catalytic process for the preparation of thiocarboxylate silane MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-12-08 US claimed
CN-105102465-A Catalytic process for the preparation of thiocarboxylate silane MOMENTIVE PERFORMANCE MAT INC 2015-11-25 CN claimed
US-20050245754-A1 Process for manufacture of blocked mercaptosilane coupling agents MOMENTIVE PERFORMANCE MATERIALS INC. 2005-11-03 US claimed
EP-1560836-A1 PROCESS FOR MANUFACTURE OF BLOCKED MERCAPTOSILANE COUPLING AGENTS GENERAL ELECTRIC COMPANY (US) 2005-08-10 EP claimed
WO-2005007660-A1 PROCESS FOR MANUFACTURE OF BLOCKED MERCAPTOSILANE COUPLING AGENTS GENERAL ELECTRIC COMPANY (US) 2005-01-27 WO claimed
US-6777569-B1 REACTING POLYSULFANE-CONTAINING ORGANOSILICON COMPOUND WITH ALKALI OR ALKALINE EARTH METAL OR COMPOUND, REACTING METAL SALT WITH AN ACYL HALIDE OR CARBONYL DIHALIDE GENERAL ELECTRIC COMPANY 2004-08-17 US claimed
US-6683135-B2 FOR USE IN TIRES, SHOE SOLES MOMENTIVE PERFORMANCE MATERIALS INC. 2004-01-27 US claimed
US-20030225195-A1 Silicon compounds such as 2-triethoxysilyl-1-ethylthioacetate, used as binders of rubbers such as butadiene-styrene copolymers, containing fillers CROMPTON CORPORATION 2003-12-04 US claimed
EP-0958298-B1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS CROMPTON CORP (US) 2003-05-07 EP claimed
US-6528673-B2 Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification CROMPTON CORPORATION 2003-03-04 US claimed
US-20020099118-A1 For use in tires, shoe soles WITCO CORPORATION, A CORPORATION OF THE STATE OF DELAWARE 2002-07-25 US claimed
US-20020055646-A1 Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification WITCO CORPORATION 2002-05-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919920-B2 Method for the manufacture of alkoxysilyl-containing thiocarboxylic acid esters TST, MPST, APEH LMNA 4244/4885CA12 349/4885CA1 709/4885
US-20200347084-A1 METHOD FOR THE MANUFACTURE OF ALKOXYSILYL-CONTAINING THIOCARBOXYLIC ACID ESTERS TST, MPST, APEH LMNA 4244/4885CA12 349/4885CA1 709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.