Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 19/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3302052 | 0.82 | ADORA2A (0.73) | ADORA2AADORA1 | |
| SCHEMBL13389511 | 0.82 | ADORA2A (0.64) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3344536 | 0.82 | ADORA2A (0.64) | ADORA2AADORA1ADORA3 | |
| SCHEMBL13389582 | 0.82 | ADORA2A (0.64) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3350946 | 0.82 | ADORA2A (0.64) | ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL3298723 | 0.82 | ADORA2A (0.63) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3348936 | 0.81 | ADORA2A (0.64) | ADORA2AADORA1 | |
| SCHEMBL3344914 | 0.81 | ADORA2A (0.64) | ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL3345134 | 0.79 | ADORA2A (0.67) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3301164 | 0.78 | ADORA2A (1.00) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045015-A1 | HETEROARYL SUBSTITUTED THIENO[2,3-D]PYRIMIDINE AND THEIR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-22 | — | — | WO | disclosed |