Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353497 | 0.82 | MAPT (0.36) | MAPTL3MBTL1TP53NPSR1 | |
| SCHEMBL31567504 | 0.81 | MAPT (0.37) | MAPTL3MBTL1TP53 | |
| SCHEMBL15738047 | 0.81 | MAPT (0.36) | MAPTL3MBTL1 | |
| SCHEMBL15802703 | 0.79 | MAPT (0.36) | MAPTL3MBTL1TP53NPSR1 | |
| SCHEMBL12539265 | 0.78 | MMP8 (0.36) | MAPT | |
| SCHEMBL543811 | 0.78 | MAPT (0.35) | MAPTL3MBTL1TP53 | |
| SCHEMBL3371032 | 0.78 | MAPT (0.35) | MAPTNPSR1 | |
| SCHEMBL3531184 | 0.76 | MAPT (0.34) | MAPT | |
| SCHEMBL3370002 | 0.76 | MAPT (0.34) | MAPT | |
| SCHEMBL18489636 | 0.76 | MAPT (0.34) | MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160411-A1 | BENZOXATHIINE AND BENZOXATHIOLE DERIVATIVES AND USES THEREOF | WYETH (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2008052078-A2 | BENZOXATHIINE AND BENZOXATHIOLE DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160411-A1 | BENZOXATHIINE AND BENZOXATHIOLE DERIVATIVES AND USES THEREOF | HTR2C, HTR3B, HTR1A | MAPT 2428/4885L3MBTL1 3630/4885TP53 4430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.