Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344914 | 0.82 | ADORA2A (0.64) | ADORA2AADORA1 | |
| SCHEMBL3350940 | 0.81 | ADORA2A (0.56) | ADORA2AADORA1 | |
| SCHEMBL3348932 | 0.80 | ADORA2A (0.64) | ADORA2AADORA1 | |
| SCHEMBL3344536 | 0.80 | ADORA2A (0.64) | ADORA2AADORA1 | |
| SCHEMBL3302953 | 0.75 | ADORA2A (0.57) | ADORA2AADORA1 | |
| SCHEMBL3304186 | 0.73 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL3305685 | 0.69 | ADORA2A (0.73) | ADORA2AADORA1 | |
| SCHEMBL3302454 | 0.68 | ADORA2A (0.67) | ADORA2AADORA1 | |
| SCHEMBL3345262 | 0.67 | ADORA2A (0.56) | ADORA2AADORA1 | |
| SCHEMBL3299843 | 0.66 | ADORA2A (0.71) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045015-A1 | HETEROARYL SUBSTITUTED THIENO[2,3-D]PYRIMIDINE AND THEIR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-22 | — | — | WO | disclosed |