Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 15/20 | 0.64 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297128 | 0.82 | ADORA2A (0.74) | ADORA2AADORA1 | |
| SCHEMBL3348936 | 0.82 | ADORA2A (0.64) | ADORA2AADORA1PDE10A | |
| SCHEMBL3344536 | 0.81 | ADORA2A (0.64) | ADORA2AADORA1 | |
| SCHEMBL13389506 | 0.81 | ADORA2A (0.64) | ADORA2AADORA1PDE10A | |
| SCHEMBL3350940 | 0.80 | ADORA2A (0.56) | ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL3298338 | 0.80 | ADORA2A (0.63) | ADORA2AADORA1PDE10A | |
| SCHEMBL3344910 | 0.80 | ADORA2A (0.57) | ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL3345119 | 0.79 | ADORA2A (0.63) | ADORA2AADORA1PDE10A | |
| SCHEMBL3303514 | 0.79 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL13389260 | 0.77 | ADORA2A (0.59) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045015-A1 | HETEROARYL SUBSTITUTED THIENO[2,3-D]PYRIMIDINE AND THEIR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-22 | — | — | WO | disclosed |