SCHEMBL3345175

SCHEMBL3345175

Cc1nc(S(C)(=O)=O)ccc1N(C)Cc1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 18/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3343172 0.82 GPR119 (0.55) GPR119
SCHEMBL3340657 0.81 GPR119 (0.60) GPR119
SCHEMBL3344227 0.81 GPR119 (0.53) GPR119
SCHEMBL3342662 0.78 GPR119 (0.53) GPR119
SCHEMBL3343199 0.78 GPR119 (0.55) GPR119
SCHEMBL3376773 0.76 GPR119 (0.54) GPR119
SCHEMBL13324476 0.76 GPR119 (0.91) GPR119
SCHEMBL31681035 0.76 GPR119 (0.60) GPR119
SCHEMBL3347332 0.76 GPR119 (0.65) GPR119
SCHEMBL3342560 0.75 GPR119 (0.55) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010048149-A2 HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE KALYPSYS, INC. (US) 2010-04-29 WO disclosed