SCHEMBL3347332

SCHEMBL3347332

CC(C)(C)OC(=O)N1CCC(Oc2ccc(COS(C)(=O)=O)cc2)CC1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 16/20 0.65
HRH3 Q9Y5N1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19838571 0.86 GPR119 (0.60) GPR119HRH3
SCHEMBL3342643 0.84 GPR119 (0.57) GPR119
SCHEMBL23373231 0.83 GPR119 (0.63) GPR119HRH3
SCHEMBL3342716 0.83 GPR119 (0.66) GPR119HRH3
SCHEMBL13324476 0.82 GPR119 (0.91) GPR119
SCHEMBL22533161 0.82 GPR119 (0.61) GPR119HRH3
SCHEMBL3342725 0.82 GPR119 (0.61) GPR119HRH3
SCHEMBL28504355 0.82 GPR119 (0.61) GPR119HRH3
SCHEMBL3344947 0.82 GPR119 (0.61) GPR119HRH3
SCHEMBL74203 0.82 GPR119 (0.67) GPR119HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010048149-A2 HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE KALYPSYS, INC. (US) 2010-04-29 WO disclosed