SCHEMBL3345222

SCHEMBL3345222

COc1cccc(C2=N[C](c3ccccc3Cl)N=C2c2cccc(OC)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASR P41180 1/20 0.44
DYRK1A Q13627 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
MAOB P27338 1/20 0.43
CASP3 P42574 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
CCNE2 O96020 1/20 0.43
CCNE1 P24864 1/20 0.43
CDK2 P24941 1/20 0.43
BTK Q06187 1/20 0.42
MAPT P10636 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CHRM4 P08173 1/20 0.41
DRD2 P14416 1/20 0.41
HTR7 P34969 1/20 0.41
PDE4A P27815 1/20 0.41
PDE4B Q07343 1/20 0.41
PDE4C Q08493 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7579760 0.82 CASR (0.58) CASRDYRK1ACLK4MAOBCASP3
SCHEMBL1132054 0.77 CYP2A6 (0.58) CASP3SENP8SENP7SENP6SMN1; SMN2
SCHEMBL21906379 0.76 BTK (0.42) CASRDYRK1ACLK4MAOBCASP3
SCHEMBL27631023 0.73 CASR (0.53) CASRDYRK1ACLK4MAOBBTK
SCHEMBL7898893 0.73 ADORA2A (0.44) CASRMAOBCASP3SENP8SENP7
SCHEMBL29732632 0.73 ADORA2A (0.44) CASRMAOBCASP3SENP8SENP7
SCHEMBL2020140 0.73 ABL1 (0.59) DYRK1ACLK4MAOBSMN1; SMN2ADORA2A
SCHEMBL28866454 0.73 CYP1A1 (0.53) CASRDYRK1ACLK4MAOBADORA2A
SCHEMBL29660677 0.72 DYRK1A (0.43) CASRDYRK1ACLK4CASP3SENP8
SCHEMBL28338943 0.72 HTR7 (0.55) CHRM4DRD2HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11939412-B2 Curable composition, antifogging coating agent, and cured film TOKYO OHKA KOGYO CO., LTD. (JP) 2024-03-26 US disclosed
US-20220325024-A1 CURABLE COMPOSITION, ANTIFOGGING COATING AGENT, AND CURED FILM TOKYO OHKA KOGYO CO., LTD. (JP) 2022-10-13 US disclosed
US-20200308325-A1 COMPOSITION AND METHOD FOR FORMING INSULATING PART TOKYO OHKA KOGYO CO., LTD. (JP) 2020-10-01 US disclosed
US-20200139433-A1 METHOD FOR PRODUCING SURFACE-MODIFIED METAL OXIDE FINE PARTICLE, METHOD FOR PRODUCING IMPROVED METAL OXIDE FINE PARTICLES, SURFACE-MODIFIED METAL OXIDE FINE PARTICLES, AND METAL OXIDE FINE PARTICLE DISPERSION LIQUID TOKYO OHKA KOGYO CO., LTD. (JP) 2020-05-07 US disclosed
US-20100159691-A1 PHOTOSENSITIVE RESIN COMPOSITION AND LAMINATE ASAHI KASEI EMD CORPORATION (JP) 2010-06-24 US disclosed