Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11185194 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDMAPK1GLA | |
| SCHEMBL3919799 | 0.82 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDMAPK1GLA | |
| SCHEMBL21128646 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDMAPK1GLA | |
| SCHEMBL22468394 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMAPK1GLA | |
| SCHEMBL11192364 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDMAPK1GLA | |
| SCHEMBL13898734 | 0.76 | DHODH (0.51) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL6384779 | 0.75 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDMAPK1GLA | |
| SCHEMBL21971963 | 0.73 | KDM4E (0.46) | ALDH1A1KDM4EHPGDMAPK1GLA | |
| SCHEMBL25308960 | 0.72 | CTNNB1 (0.38) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL28483930 | 0.72 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDMAPK1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102202505-A | Method for improving plant health | BASF SE | 2011-09-28 | — | — | CN | claimed |
| WO-2010049405-A1 | METHOD FOR IMPROVING PLANT HEALTH | BASF SE (DE) | 2010-05-06 | — | — | WO | claimed |
| CN-106414434-B | Isothiazole derivatives as GPR120 agonists for the treatment of type II diabetes | 詹森药业有限公司 | 2019-12-31 | — | — | CN | disclosed |
| CN-108938625-A | Purposes and preparation method of the 2- virtue formamido thiophene -3- carboxylic acid derivative as ANO1 protein inhibitor | 北京大学 | 2018-12-07 | — | — | CN | disclosed |
| CN-102202505-A | Method for improving plant health | BASF SE | 2011-09-28 | — | — | CN | disclosed |
| WO-2010049405-A1 | METHOD FOR IMPROVING PLANT HEALTH | BASF SE (DE) | 2010-05-06 | — | — | WO | disclosed |
| US-7501530-B2 | Trifluoromethyl-thiophene carboxylic acid aniledes and use thereof as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2009-03-10 | — | — | US | disclosed |
| US-20060172891-A1 | Trifluoromethyl-thiophene carboxylic acid aniledes and use thereof as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-03 | — | — | US | disclosed |
| CN-1764657-A | Trifluoromethyl-thiophene carboxylic acid anilides and use thereof as fungicides. | BASF AG (DE) | 2006-04-26 | — | — | CN | disclosed |
| EP-1608637-A1 | TRIFLUOROMETHYL-THIOPHENE CARBOXYLIC ACID ANILIDES AND USE THEREOF AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004085419-A1 | TRIFLUOROMETHYL-THIOPHENE CARBOXYLIC ACID ANILIDES AND USE THEREOF AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060172891-A1 | Trifluoromethyl-thiophene carboxylic acid aniledes and use thereof as fungicides | AS3MT, GABBR1, TH | ALDH1A1 257/4885KDM4E 273/4885HPGD 4736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.