Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21128647 | 0.85 | PPARA (0.40) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL28483930 | 0.84 | ALDH1A1 (0.45) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL21128646 | 0.81 | ALDH1A1 (0.51) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL22468394 | 0.79 | ALDH1A1 (0.50) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL20852786 | 0.73 | NPC1 (0.41) | KDM4EALDH1A1HPGDMAPK1MEN1 | |
| SCHEMBL18869401 | 0.73 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL3345343 | 0.73 | ALDH1A1 (0.43) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL13868022 | 0.71 | RIPK1 (0.39) | ALDH1A1MEN1KMT2ARIPK1RAB9A | |
| SCHEMBL11185194 | 0.70 | ALDH1A1 (0.41) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL14234964 | 0.70 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3439477-B1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-06 | — | — | EP | disclosed |