SCHEMBL3345348

SCHEMBL3345348

COC(CC[Si](OC)(OC)OC)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 6/20 0.41
SLC6A4 P31645 6/20 0.41
CYP1A2 P05177 4/20 0.41
CYP3A4 P08684 4/20 0.41
CYP2D6 P10635 4/20 0.41
TSHR P16473 3/20 0.41
SLC6A3 Q01959 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
CYP2C19 P33261 1/20 0.41
PMP22 Q01453 2/20 0.40
GSR P00390 1/20 0.35
HTR2C P28335 3/20 0.34
HTR2B P41595 3/20 0.34
AOC3 Q16853 2/20 0.34
CHRM1 P11229 2/20 0.34
ADRA2B P18089 2/20 0.34
HTR2A P28223 2/20 0.34
HRH1 P35367 2/20 0.34
OPRM1 P35372 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3345553 0.84 SLC6A4 (0.37) SLC6A2SLC6A4CYP1A2CYP3A4CYP2D6
SCHEMBL3342082 0.84 SLC6A4 (0.37) SLC6A2SLC6A4CYP1A2CYP3A4CYP2D6
SCHEMBL1532968 0.81 SLC6A4 (0.38) SLC6A2SLC6A4CYP1A2CYP3A4CYP2D6
SCHEMBL28330761 0.81 SLC6A4 (0.36) SLC6A2SLC6A4CYP1A2CYP3A4CYP2D6
SCHEMBL9167147 0.78 TSHR (0.37) SLC6A2SLC6A4CYP1A2CYP3A4CYP2D6
SCHEMBL37639 0.78 SCN4A (0.43)
SCHEMBL28128614 0.76 SCN4A (0.42)
SCHEMBL1098807 0.76 AOC3 (0.43) SLC6A2SLC6A4CYP1A2CYP3A4CYP2D6
SCHEMBL5200492 0.75 SCN1A (0.35) SLC6A2SLC6A4CYP1A2CYP3A4CYP2D6
SCHEMBL1307453 0.75 CHRNB2 (0.49) KMT2AMEN1HTR2AHRH1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100151188-A1 STRUCTURE HAVING ORGANIC-INORGANIC COMPOSITE LAYER AND METHOD OF MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2010-06-17 US disclosed
US-20090239086-A1 MICROPHASE-SEPARATED STRUCTURE ON FLEXIBLE SUBSTRATE, AND METHOD OF MANUFACTURE THEREOF FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed