SCHEMBL9167147

SCHEMBL9167147

CO[Si](CCC(Cl)c1ccccc1)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A3 Q01959 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
SLC6A4 P31645 1/20 0.34
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
HTR2A P28223 2/20 0.33
HRH1 P35367 2/20 0.33
CASR P41180 2/20 0.33
LMNA P02545 2/20 0.33
ALOX12 P18054 2/20 0.33
HTT P42858 2/20 0.33
PMP22 Q01453 1/20 0.33
MTNR1A P48039 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10596573 0.82 POLB (0.37) TSHRSLC6A2HTR2AHRH1LMNA
SCHEMBL3345348 0.78 SLC6A2 (0.41) TSHRMEN1KMT2ASLC6A2SLC6A3
SCHEMBL37639 0.78 SCN4A (0.43) ALDH1A1
SCHEMBL28128614 0.76 SCN4A (0.42) ALDH1A1
SCHEMBL10599884 0.76 TSHR (0.42) TSHRSLC6A2SLC6A3SLC6A4HTR2A
SCHEMBL1307453 0.75 CHRNB2 (0.49) MEN1KMT2AHTR2AHRH1
SCHEMBL5200492 0.75 SCN1A (0.35) TSHRMEN1KMT2ASLC6A2SLC6A3
SCHEMBL22042229 0.75 TSHR (0.55) TSHRHTR2AHRH1
SCHEMBL8682047 0.75 HPGD (0.41) TSHRKMT2ASLC6A2SLC6A3CYP1A2
SCHEMBL5163795 0.74 MEN1 (0.32) TSHRMEN1KMT2ASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111364112-A Deodorizing fiber 南亚塑胶工业股份有限公司 2020-07-03 CN disclosed
EP-0435004-B1 Siloxanes useful in permanent waving of hair DOW CORNING (US) 1995-03-01 EP disclosed
US-5162479-A Siloxanes useful in permanent waving of hair DOW CORNING CORPORATION (US) 1992-11-10 US disclosed
US-5061482-A Siloxanes useful in permanent waving of hair DOW CORNING CORPORATION (US) 1991-10-29 US disclosed
US-5045310-A Siloxanes useful in permanent waving of hair DOW CORNING CORPORATION (US) 1991-09-03 US disclosed
EP-0435004-A1 Siloxanes useful in permanent waving of hair DOW CORNING CORPORATION (US) 1991-07-03 EP disclosed
EP-0191929-B1 COUPLING AGENT FOR THE PREPARATION OF VULCANISATES HAVING A GOOD FILLER-RUBBER ADHESION HÜLS AKTIENGESELLSCHAFT (DE) 1989-05-03 EP disclosed
US-4681961-A OLIGOSULFANE HUELS AKTIENGESELLSCHAFT (DE) 1987-07-21 US disclosed
EP-0191929-A1 Coupling agent for the preparation of vulcanisates having a good filler-rubber adhesion HÜLS AKTIENGESELLSCHAFT (DE) 1986-08-27 EP disclosed