Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.46 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.46 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345552 | 1.00 | MAPK1 (0.64) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL301282 | 0.83 | ALDH1A1 (0.56) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL3123070 | 0.80 | ALDH1A1 (0.60) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL10793484 | 0.79 | ALDH1A1 (0.47) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL8982833 | 0.79 | ALDH1A1 (1.00) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| Dimethyl Yellow SCHEMBL187589 | 0.79 | ALDH1A1 (1.00) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL10909165 | 0.79 | ALDH1A1 (1.00) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL8982839 | 0.79 | ALDH1A1 (1.00) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL8982830 | 0.79 | ALDH1A1 (1.00) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL180055 | 0.79 | ALDH1A1 (0.67) | MAPK1ALDH1A1TDP1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |