Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 4/20 | 1.00 |
| ▸ | TSHR | P16473 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | RAB9A | P51151 | 7/20 | 0.66 |
| ▸ | NPC1 | O15118 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | NSD2 | O96028 | 1/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.66 |
| ▸ | ALPL | P05186 | 2/20 | 0.63 |
| ▸ | ALPG | P10696 | 2/20 | 0.63 |
| ▸ | ALPI | P09923 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909165 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPK1TSHRTDP1HSD17B10 | |
| SCHEMBL8982830 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPK1TSHRTDP1HSD17B10 | |
| Dimethyl Yellow SCHEMBL187589 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPK1TSHRTDP1HSD17B10 | |
| SCHEMBL8982839 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPK1TSHRTDP1HSD17B10 | |
| Methyl Yellow SCHEMBL239712 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPK1TSHRTDP1HSD17B10 | |
| Dimethyl Yellow SCHEMBL6240921 | 0.98 | ALDH1A1 (0.95) | ALDH1A1MAPK1TSHRTDP1HSD17B10 | |
| Methyl Yellow SCHEMBL6240923 | 0.98 | ALDH1A1 (0.95) | ALDH1A1MAPK1TSHRTDP1HSD17B10 | |
| Methyl Yellow SCHEMBL28233507 | 0.98 | ALDH1A1 (0.95) | ALDH1A1MAPK1TSHRTDP1HSD17B10 | |
| SCHEMBL9207409 | 0.94 | ALDH1A1 (0.88) | ALDH1A1MAPK1TSHRTDP1HSD17B10 | |
| Methyl Yellow SCHEMBL28067007 | 0.94 | ALDH1A1 (0.88) | ALDH1A1MAPK1TSHRTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9803240-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-9139610-B2 | Dark quenchers for donor-acceptor energy transfer | BIOSEARCH TECHNOLOGIES, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150197792-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | BIOSEARCH TECHNOLOGIES, INC. | 2015-07-16 | — | — | US | disclosed |
| US-9018369-B2 | Dark quenchers for donor-acceptor energy transfer | BIOSEARCH TECHNOLOGIES, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-8946404-B2 | Dark quenchers for donor-acceptor energy transfer | BIOSEARCH TECHNOLOGIES, INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140323703-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | BIOSEARCH TECHNOLOGIES, INC. | 2014-10-30 | — | — | US | disclosed |
| US-20140316118-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | BIOSEARCH TECHNOLOGIES, INC. | 2014-10-23 | — | — | US | disclosed |
| US-20140194611-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-20140187763-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | BIOSEARCH TECHNOLOGIES, INC. | 2014-07-03 | — | — | US | disclosed |
| US-8674094-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-20100021922-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | BIOSEARCH TECHNOLOGIES, INC. (US) | 2010-01-28 | — | — | US | disclosed |
| US-7635762-B2 | Luminescent metal ion complexes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2009-12-22 | — | — | US | disclosed |
| US-20090259030-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES (US) | 2009-10-15 | — | — | US | disclosed |
| US-7582432-B2 | Multiplexing methods using dark quenchers, nonfluorescing disazo dyes, functionalized for their rapid attachment to probe components; engineered to have a desired light absorption profile; facilitate interaction between quencher and fluorophore without form nucleic acid secondary structure | BIOSEARCH TECHNOLOGIES, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-20070154898-A1 | Multiplexing methods using dark quenchers, nonfluorescing disazo dyes, functionalized for their rapid attachment to probe components; engineered to have a desired light absorption profile; facilitate interaction between quencher and fluorophore without form nucleic acid secondary structure | BIOSEARCH TECHNOLOGIES, INC. (US) | 2007-07-05 | — | — | US | disclosed |
| EP-0332455-B1 | Photosensitive material and image forming method | CANON KK (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5041369-A | Silver Halide, Silver Salt, Reducing Agent, Metal or Organic Dye | CANON KABUSHIKI KAISHA (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0332455-A2 | Photosensitive material and image forming method | CANON KABUSHIKI KAISHA (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4624532-A | IMPROVED COLOR FOR ELECTRO-OPTICAL DISPLAYS | GENERAL ELECTRIC COMPANY (US) | 1986-11-25 | — | — | US | disclosed |
| US-4356102-A | Dichroic liquid crystal compositions containing anthraquinone-based dyes | GENERAL ELECTRIC COMPANY (US) | 1982-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259030-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | DDX1, DDX18, DDX3X | ALDH1A1 1107/4885MAPK1 4785/4885TSHR 1248/4885 |
| US-20140323703-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | NQO1, BLVRB, SQOR | ALDH1A1 1120/4885MAPK1 4418/4885TSHR 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.