Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043506 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2APOLBSIGMAR1 | |
| SCHEMBL10426714 | 0.70 | KMT2A (0.43) | ALDH1A1MAPTKMT2APOLBSIGMAR1 | |
| SCHEMBL10426713 | 0.69 | KMT2A (0.43) | ALDH1A1MAPTKMT2APOLBSIGMAR1 | |
| SCHEMBL16411512 | 0.69 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2APOLBSIGMAR1 | |
| SCHEMBL12805538 | 0.68 | CNR1 (0.43) | ALDH1A1MAPTKMT2AKDM4EKDM4A | |
| SCHEMBL10425888 | 0.68 | POLB (0.48) | ALDH1A1MAPTKMT2APOLBSIGMAR1 | |
| SCHEMBL4929767 | 0.68 | KLK7 (0.42) | ALDH1A1MAPTKMT2APOLBSIGMAR1 | |
| SCHEMBL10426684 | 0.68 | POLB (0.47) | ALDH1A1MAPTKMT2APOLBSIGMAR1 | |
| SCHEMBL10425887 | 0.68 | POLB (0.47) | ALDH1A1MAPTKMT2APOLBSIGMAR1 | |
| SCHEMBL3373579 | 0.67 | PARP1 (0.50) | ALDH1A1MAPTKMT2APOLBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038081-A2 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2010-04-08 | — | — | WO | disclosed |