SCHEMBL3373579

SCHEMBL3373579

NC(=O)c1ccc(C(N)=O)c(CCN2CCOCC2)c1CCN1CCOCC1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.50
PARP2 Q9UGN5 2/20 0.50
ALDH1A1 P00352 5/20 0.49
KDM4E B2RXH2 3/20 0.49
KMT2A Q03164 5/20 0.45
MAPT P10636 4/20 0.45
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
SIGMAR1 Q99720 1/20 0.43
LMNA P02545 2/20 0.42
MPI P34949 1/20 0.42
CYP2C19 P33261 1/20 0.42
GLA P06280 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2463886 0.91 PARP1 (0.46) PARP1PARP2ALDH1A1KDM4EKMT2A
SCHEMBL18040375 0.91 PARP1 (0.57) PARP1PARP2ALDH1A1KDM4EKMT2A
SCHEMBL8722296 0.89 PARP1 (0.44) PARP1PARP2ALDH1A1KDM4EKMT2A
SCHEMBL9760982 0.86 PARP1 (0.44) PARP1PARP2ALDH1A1KDM4EKMT2A
SCHEMBL8722305 0.81 PARP1 (0.45) PARP1PARP2ALDH1A1KDM4EKMT2A
SCHEMBL487963 0.80 ALDH1A1 (0.56) PARP1PARP2ALDH1A1KDM4EKMT2A
SCHEMBL7527710 0.79 MEN1 (0.54) PARP1PARP2ALDH1A1KDM4EKMT2A
SCHEMBL10607328 0.79 KMT2A (0.49) ALDH1A1KDM4EKMT2AMAPTCNR1
SCHEMBL7527733 0.77 PARP1 (0.53) PARP1PARP2ALDH1A1KDM4EKMT2A
SCHEMBL377882 0.77 SIGMAR1 (0.54) PARP1PARP2ALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100039028-A1 DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-02-18 US disclosed
US-20010002415-A1 Pigment composition and colored photosensitive composition TAKEDA AKIHIKO (JP) 2001-05-31 US disclosed
US-6194480-B1 BINDER POLYMER, MULTIFUNCTIONAL POLY-UNSATURATED MONOMER, PHOTOPOLYMERIZATION INITIATOR, AND ORGANIC PIGMENT, DISPERSANT COPOLYMER OF POLYMERIZABLE OLIGOMER AND NITROGEN CONTAINING UNSATURATED MONOMER, AND AN ORGANIC SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 2001-02-27 US disclosed
US-5922122-A TRIAZINE COMPOUNDS; PAINTS, PRINTING INKS, COLOR DISPLAY PANELS; PHOTOSENSITIVITY; PHOTOPOLYMERIZABLE MONOMER AND ACIDIC POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1999-07-13 US disclosed
EP-0870809-A2 Pigment composition and colored photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1998-10-14 EP disclosed